Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Costs of delivering human papillomavirus vaccination to schoolgirls in Mwanza Region, Tanzania
BMC Medicine, Volume 10, Article 137, Year 2012
Notification
URL copied to clipboard!
Description
Background: Cervical cancer is the leading cause of female cancer-related deaths in Tanzania. Vaccination against human papillomavirus (HPV) offers a new opportunity to control this disease. This study aimed to estimate the costs of a school-based HPV vaccination project in three districts in Mwanza Region (NCT ID: NCT01173900), Tanzania and to model incremental scaled-up costs of a regional vaccination program.Methods: We first conducted a top-down cost analysis of the vaccination project, comparing observed costs of age-based (girls born in 1998) and class-based (class 6) vaccine delivery in a total of 134 primary schools. Based on the observed project costs, we then modeled incremental costs of a scaled-up vaccination program for Mwanza Region from the perspective of the Tanzanian government, assuming that HPV vaccines would be delivered through the Expanded Programme on Immunization (EPI).Results: Total economic project costs for delivering 3 doses of HPV vaccine to 4,211 girls were estimated at about US$349,400 (including a vaccine price of US$5 per dose). Costs per fully-immunized girl were lower for class-based delivery than for age-based delivery. Incremental economic scaled-up costs for class-based vaccination of 50,290 girls in Mwanza Region were estimated at US$1.3 million. Economic scaled-up costs per fully-immunized girl were US$26.41, including HPV vaccine at US$5 per dose. Excluding vaccine costs, vaccine could be delivered at an incremental economic cost of US$3.09 per dose and US$9.76 per fully-immunized girl. Financial scaled-up costs, excluding costs of the vaccine and salaries of existing staff were estimated at US$1.73 per dose.Conclusions: Project costs of class-based vaccination were found to be below those of age-based vaccination because of more eligible girls being identified and higher vaccine uptake. We estimate that vaccine can be delivered at costs that would make HPV vaccination a very cost-effective intervention. Potentially, integrating HPV vaccine delivery with cost-effective school-based health interventions and a reduction of vaccine price below US$5 per dose would further reduce the costs per fully HPV-immunized girl. © 2012 Quentin et al; licensee BioMed Central Ltd.
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC3520755/bin/1741-7015-10-137-S1.DOC
https://efashare.b-cdn.net/share/pmc/articles/PMC3520755/bin/1741-7015-10-137-S2.PDF
https://efashare.b-cdn.net/share/pmc/articles/PMC3520755/bin/1741-7015-10-137-S3.PDF
Authors & Co-Authors
Quentin, Wilm
Unknown Affiliation
Terris-Prestholt, Fern
Unknown Affiliation
Changalucha, John M.
Unknown Affiliation
Soteli, Selephina
Unknown Affiliation
Edmunds, William John
Unknown Affiliation
Hutubessy, Raymond Christiaan W.
Unknown Affiliation
Ross, David Anthony
Unknown Affiliation
Kapiga, Saidi Hussein
Unknown Affiliation
Hayes, Richard John
Unknown Affiliation
Watson – Jones, Deborah
Unknown Affiliation
Statistics
Citations: 52
Authors: 10
Affiliations: 5
Identifiers
Doi:
10.1186/1741-7015-10-137
e-ISSN:
17417015
Research Areas
Cancer
Maternal And Child Health
Study Design
Randomised Control Trial
Study Locations
Tanzania
Participants Gender
Female