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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Clustered lot quality assurance sampling: A pragmatic tool for timely assessment of vaccination coverage
Tropical Medicine and International Health, Volume 16, No. 7, Year 2011
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Description
Objectives To evaluate oral poliovirus vaccine (OPV) coverage of the November 2009 round in five Northern Nigeria states with ongoing wild poliovirus transmission using clustered lot quality assurance sampling (CLQAS). Methods We selected four local government areas in each pre-selected state and sampled six clusters of 10 children in each Local Government Area, defined as the lot area. We used three decision thresholds to classify OPV coverage: 75-90%, 55-70% and 35-50%. A full lot was completed, but we also assessed in retrospect the potential time-saving benefits of stopping sampling when a lot had been classified. Results We accepted two local government areas (LGAs) with vaccination coverage above 75%. Of the remaining 18 rejected LGAs, 11 also failed to reach 70% coverage, of which four also failed to reach 50%. The average time taken to complete a lot was 10h. By stopping sampling when a decision was reached, we could have classified lots in 5.3, 7.7 and 7.3h on average at the 90%, 70% and 50% coverage targets, respectively. Conclusions Clustered lot quality assurance sampling was feasible and useful to estimate OPV coverage in Northern Nigeria. The multi-threshold approach provided useful information on the variation of IPD vaccination coverage. CLQAS is a very timely tool, allowing corrective actions to be directly taken in insufficiently covered areas. © 2011 Blackwell Publishing Ltd.
Authors & Co-Authors
Greenland, K.
Netherlands, Bilthoven
Rijksinstituut Voor Volksgezondheid en Milieu
Sweden, Solna
European Centre for Disease Prevention and Control
Rondy, Marc
Netherlands, Bilthoven
Rijksinstituut Voor Volksgezondheid en Milieu
Sweden, Solna
European Centre for Disease Prevention and Control
Chévez, Ana Elena
Nigeria, Abuja
Who Country Office
Sadozai, N.
Switzerland, Geneva
Organisation Mondiale de la Santé
Gasasira, Alex Ntale
Nigeria, Abuja
Who Country Office
Abanida, Emmanuel Ade
Nigeria, Abuja
National Primary Health Care Development Agency
Pate, Muhammad Ali
Nigeria, Abuja
National Primary Health Care Development Agency
Ronveaux, Olivier
Switzerland, Geneva
Organisation Mondiale de la Santé
Okayasu, Hiromasa
Switzerland, Geneva
Organisation Mondiale de la Santé
Pedalino, B.
Sweden, Solna
European Centre for Disease Prevention and Control
France, Bordeaux
French Institute for Public Health Surveillance
Pezzoli, Lorenzo
Switzerland, Geneva
Organisation Mondiale de la Santé
Statistics
Citations: 11
Authors: 11
Affiliations: 6
Identifiers
Doi:
10.1111/j.1365-3156.2011.02770.x
ISSN:
13602276
e-ISSN:
13653156
Research Areas
Health System And Policy
Maternal And Child Health
Study Locations
Nigeria