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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
HLA class I and II antigens in South African Blacks with Graves' disease
Clinical Immunology and Immunopathology, Volume 54, No. 1, Year 1990
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Description
A study was done to evaluate the relationship between Graves' disease and the HLA system in South African Blacks of Zulu descent. One hundred and three patients with Graves' disease and 1416 control subjects were typed for HLA A, B, and C antigens while HLA DR antigens were done on 63 of the former and 330 of the latter. There was a significant increase in the frequency of HLA DR3 in patients compared to control subjects (57.1% vs 36.1%; P corrected = 0.014). A relationship was also seen at the DRI locus (14.3% vs 4.6%; P corrected = 0.023). © 1990.
Authors & Co-Authors
Omar, Mahomed Abdool Khalek
South Africa, Congella
University of Natal, Faculty of Medicine
South Africa, Pinetown
Natal Institute of Immunology
South Africa, Durban
University of Kwazulu-natal
Hammond, Michael G.
South Africa, Congella
University of Natal, Faculty of Medicine
South Africa, Pinetown
Natal Institute of Immunology
South Africa, Durban
University of Kwazulu-natal
Desai, Rajesh K.
South Africa, Congella
University of Natal, Faculty of Medicine
South Africa, Pinetown
Natal Institute of Immunology
South Africa, Durban
University of Kwazulu-natal
Motala, Ayesha A.
South Africa, Congella
University of Natal, Faculty of Medicine
South Africa, Pinetown
Natal Institute of Immunology
South Africa, Durban
University of Kwazulu-natal
Aboo, Nazimuddin
South Africa, Congella
University of Natal, Faculty of Medicine
South Africa, Pinetown
Natal Institute of Immunology
South Africa, Durban
University of Kwazulu-natal
Seedat, Mohamed
South Africa, Congella
University of Natal, Faculty of Medicine
South Africa, Pinetown
Natal Institute of Immunology
South Africa, Durban
University of Kwazulu-natal
Statistics
Citations: 32
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.1016/0090-1229(90)90009-F
ISSN:
00901229