Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Trichomes, essential oil composition and biological activities of Salvia albicaulis Benth. and S. dolomitica Codd, two species from the Cape region of South Africa
South African Journal of Botany, Volume 73, No. 1, Year 2007
Notification
URL copied to clipboard!
Description
An investigation of leaf indumentum, the identification of the essential oil components and assessment of various biological activities of Salvia albicaulis and S. dolomitica essential oils were carried out. Non-glandular and both peltate and capitate glandular trichomes were identified using scanning electron microscopy. The essential oil of S. albicaulis was dominated by oxygen-containing sesquiterpenes (47%), with viridiflorol (25%), 1,8-cineole (9%) and limonene (9%) as major components. S. dolomitica oil was mainly composed of oxygen-containing monoterpenes (72%), with geraniol (20%), linalyl acetate (20%) and linalool (17%) being the major components. The in vitro pharmacological properties of the essential oils were also evaluated. Antibacterial activity was assessed against Staphylococcus aureus (ATCC 25923), Bacillus cereus (ATCC 11778), Escherichia coli (ATCC 8739) and Klebsiella pneumoniae (NCTC 9633). The oils showed poor activity against E. coli (MIC value > 32 mg ml- 1), while moderate activity was obtained against the other pathogens (MIC values between 2 and 12 mg ml- 1). The results of the antiplasmodial activity evaluated against the chloroquine-resistant FCR-3 strain showed that both S. albicaulis and S. dolomitica essential oils exhibited antiplasmodial activity with IC50 values of 6 ± 2 and 5 ± 1 μg ml- 1, respectively. The two oils also displayed anti-inflammatory activity (IC50 value: 39 ± 4 and 65 ± 6 μg ml- 1, respectively). Poor anti-oxidant activity was obtained against the DPPH·and the ABTS·+ radicals (IC50 values > 100 μg ml- 1). The toxicity profile of the two oils evaluated against the human kidney epithelium cells indicated some degree of toxicity in comparison to 5′-fluoro-uracil. © 2006 SAAB.
Authors & Co-Authors
Kamatou, Guy P.P.
South Africa, Johannesburg
University of the Witwatersrand Faculty of Health Sciences
Viljoen, Alvaro M.
South Africa, Pretoria
Tshwane University of Technology
Figueiredo, Ana Cristina
Portugal, Lisbon
Faculdade de Ciências, Universidade de Lisboa
Tilney, Patricia M.
South Africa, Johannesburg
University of Johannesburg
van Zyl, Robyn Lynne
South Africa, Johannesburg
University of the Witwatersrand Faculty of Health Sciences
Barroso, José Gonçalves
Portugal, Lisbon
Faculdade de Ciências, Universidade de Lisboa
Pedro, Luís Gaspar
Portugal, Lisbon
Faculdade de Ciências, Universidade de Lisboa
van Vuuren, Sandy
South Africa, Johannesburg
University of the Witwatersrand Faculty of Health Sciences
Statistics
Citations: 57
Authors: 8
Affiliations: 4
Identifiers
Doi:
10.1016/j.sajb.2006.08.001
ISSN:
02546299
Study Locations
South Africa