Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Two outbreaks of acute hemorrhagic conjunctivitis in Africa due to genotype III coxsackievirus A24 variant
European Journal of Clinical Microbiology and Infectious Diseases, Volume 26, No. 3, Year 2007
Notification
URL copied to clipboard!
Description
Reported here are two outbreaks of acute hemorrhagic conjunctivitis that occurred in the Democratic Republic of the Congo and in Morocco in the summers of 2003 and 2004, respectively, with a large impact on public health. Virus was isolated from the conjunctival swabs of 30 Congolese and 20 Moroccan patients. Enterovirus-specific cytopathic effect was observed in all samples. None of the strains could be typed using a conventional neutralization assay with the Melnick intersecting pools; however, by sequencing the VP1 region, the viruses could be identified as coxsackie A24 variants. Phylogenetic analysis of the 3C protease region revealed that these strains were closely related to each other as well as to genotype III isolates detected in Korea in 2002, thus proving their worldwide spread. This is the first report of an epidemic of acute hemorrhagic conjunctivitis due to a coxsackievirus A24 variant in Africa since 1987 and the first ever from Morocco. © 2007 Springer-Verlag.
Authors & Co-Authors
Lévêque, Nicolas
France, Lyon
Hopital Edouard Herriot
France, Lyon
Virologie et Pathologie Humaine
Amine, Idriss Lahlou
Morocco, Agdal Rabat
Hôpital D'instruction Des Armées Mohamed V
Cartet, Gaëlle
France, Lyon
Hopital Edouard Herriot
France, Lyon
Virologie et Pathologie Humaine
Hammani, A. B.
Morocco, Agdal Rabat
Ibn Sina Hospital, Agdal Rabat
Khazraji, Youssef Chami
Morocco, Agdal Rabat
Ministry of Health, Morocco
Lina, Bruno
France, Lyon
Hopital Edouard Herriot
France, Lyon
Virologie et Pathologie Humaine
Muyembe-Tamfum, Jean Jacques
Congo
Institut National de Recherche Biomédicale
Norder, Heléne
Sweden, Solna
Public Health Agency of Sweden
Chomel, Jean Jacques
France, Lyon
Hopital Edouard Herriot
France, Lyon
Virologie et Pathologie Humaine
Statistics
Citations: 23
Authors: 9
Affiliations: 7
Identifiers
Doi:
10.1007/s10096-007-0265-9
ISSN:
09349723
Research Areas
Genetics And Genomics
Study Locations
Congo
Morocco