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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
High yield from repeated testing for tuberculosis among high-risk citizens in Denmark
International Journal of Infectious Diseases, Volume 102, Year 2021
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Description
Background: Screening for TB (tuberculosis) among socially marginalized citizens has been implemented in many urban areas in countries with a low incidence of TB, including Denmark. This study aims to describe the findings of the screening programs for TB and latent tuberculosis (LTBI) used in the western part of Denmark in the period 2014–2019. Methods: Data was collected retrospectively on test results from interferon-gamma release assays (IGRA), spot sputum tests and chest X-rays performed as part of TB and LTBI screening among 1024 socially marginalized citizens in urban areas of western Denmark in 2014–2019. Results: The overall TB incidence was 2148/100.000 and number needed to screen to find one TB case was 39. The incidence of LTBI in the group screened using IGRA was 17.500/100.000. TB incidence when using spot sputum test was 2.5, while TB incidence when using IGRA as the primary screening test was 2.7. In total, 38.9% of TB diagnoses were obtained after the second or third round of screening. Conclusion: We demonstrated a high incidence of TB and LTBI among socially marginalized citizens in Denmark. Screening with spot sputum testing and IGRA generated comparable results in diagnosing TB in this setting. © 2020 The Authors
Authors & Co-Authors
Stærke, Nina Breinholt
Denmark, Aarhus
Aarhus Universitetshospital
Denmark, Aarhus
Aarhus Universitet
Wejse, Christian
Denmark, Aarhus
Aarhus Universitetshospital
Denmark, Aarhus
Aarhus Universitet
Hilberg, Ole
Denmark, Vejle
Sygehus Lillebælt - Vejle
Denmark, Odense
Syddansk Universitet
Fløe, Andreas
Denmark, Aarhus
Aarhus Universitetshospital
Statistics
Citations: 5
Authors: 4
Affiliations: 7
Identifiers
Doi:
10.1016/j.ijid.2020.10.076
ISSN:
12019712
Research Areas
Infectious Diseases
Study Design
Cohort Study