The spheno-occipital synchondrosis and morphometry of sella turcica association with different phenotype factors related to ectopic eye tooth/teeth

Objectives: This study investigates the prevalence of Spheno-Occipital Synchondrosis (SOS) and sella turcica morphometry (STM) association with different phenotype factors related to ectopic eye tooth/teeth (EET) using cone beam computed tomography (CBCT) imaging. Methods: This comparative retrospective study analyzed 252 CBCT images. Subjects in the EET group consisted of 197 CBCT images with the phenotype factor in number, i.e., unilateral (13, n = 62; 23, n = 59) or bilateral (1323, n = 76) and matched control (n = 55). SOS and STM were investigated using 3D OnDemand Software. Seven parameters of STM were measured. To test the association X2 used for SOS prevalence, disparities in STM were tested using ANOVA and post hoc Tukey test. Results: The prevalence of unfused SOS was 48.4% and 16.1% in the 1323 and control groups, respectively. Fused SOS prevalence was quite similar in all four groups. Phenotype factor in number, i.e., unilateral 13, 23, or bilateral EET group showed significant disparities in six out of seven parameters (p = 0.044 to p ≥ 0.001). Additionally, phenotype factor in position, i.e., occlusal, buccal, or palatal group showed insignificant disparities (p = 0.463 to p = 1.00). Conclusion: SOS in the ectopic eye tooth group (EETG) was prevalent in the 1323 and buccal position groups. Differing from previous two-dimensional (2D) studies, there were statistically significant disparities in all seven measured variables of STM among control, and three different phenotype factors in numbers were revealed using three-dimensional (3D) CBCT imaging.