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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Management and treatment outcomes of patients enrolled in MDR-TB treatment in Viet Nam
Public Health Action, Volume 6, No. 1, Year 2016
Notification
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Description
Setting: The programmatic management of drug-resistant tuberculosis (TB) in Viet Nam has been rapidly scaled up since 2009. Objectives: To document the annual numbers of patients enrolled for multidrug-resistant tuberculosis (MDR-TB) treatment during 2010–2014 and to determine characteristics and treatment outcomes of patients initiating treatment during 2010–2012. Design: A retrospective cohort study using national reports and data from the national electronic data system for drug-resistant TB. Results: The number of patients enrolled annually for MDR-TB treatment increased from 97 in 2010 to 1522 in 2014. The majority of patients were middle-aged men who had pulmonary disease and had failed a retreatment regimen; 77% had received ≥2 courses of TB treatment. Favourable outcomes (cured and treatment completed) were attained in 73% of patients. Unfavourable outcomes included loss to follow-up (12.5%), death (8%) and failure (6.3%). Having had ≥2 previous treatment courses and being human immunodeficiency virus-positive were associated with unfavourable outcomes. Conclusion: Increasing numbers of patients are being treated for MDR-TB each year with good treatment outcomes under national programme management in Viet Nam. However, there is a need to increase case detection— currently at 30% of the estimated 5100 MDR-TB cases per year, reduce adverse outcomes and improve monitoring and evaluation. © 2016 The Union.
Authors & Co-Authors
Nguyen, Nhung Viet
Viet Nam, Hanoi
Vietnam National University, Hanoi
Hoà, Nguyen Binh
Viet Nam, Hanoi
Vietnam National University, Hanoi
France, Paris
International Union Against Tuberculosis and Lung Disease
Takarinda, Kudakwashe Collin
France, Paris
International Union Against Tuberculosis and Lung Disease
Tayler-Smith, Katie
Switzerland, Geneva
Medecins Sans Frontieres
Harries, Anthony David
France, Paris
International Union Against Tuberculosis and Lung Disease
United Kingdom, London
London School of Hygiene & Tropical Medicine
Statistics
Citations: 13
Authors: 5
Affiliations: 4
Identifiers
Doi:
10.5588/pha.15.0068
ISSN:
22208372
Research Areas
Infectious Diseases
Study Design
Cohort Study
Study Approach
Quantitative
Participants Gender
Male