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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Arthritis in association with human immunodeficiency virus infection in Black African children: Causal or coincidental?
Rheumatology, Volume 44, No. 7, Year 2005
Notification
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Description
Objectives. To compare human immunodeficiency virus (HIV)-infected and HIV-uninfected children with arthritis of unknown origin to determine whether the association between HIV infection and arthritis is causal or coincidental. Method. Retrospective review of 132 children with arthritis who were tested for HIV infection. Results. Thirty-five (27%) of the children were HIV infected and the male to female ratio was 2.5:1 (P = 0.02). Arthritis was the presenting feature of HIV infection in 78% of these children. The remaining 97 (73%) were diagnosed as having juvenile idiopathic arthritis. 'Spondyloarthropathy-like' features were found in 34% of HIV-infected children compared with 5% of uninfected children. Conclusion. The high prevalence of HIV infection in 27% of children, the predominance of males and the increased prevalence of 'spondyloarthropathy-like' features, supports a causal relationship between HIV infection and arthritis. © The Author 2005. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved.
Authors & Co-Authors
Chinniah, Kogielambal
South Africa, Durban
The Nelson R. Mandela Medical School
Mody, Girish M.
South Africa, Durban
The Nelson R. Mandela Medical School
Bhimma, Rajendra
South Africa, Durban
The Nelson R. Mandela Medical School
Adhikari, Mirriam A.
South Africa, Durban
The Nelson R. Mandela Medical School
Statistics
Citations: 44
Authors: 4
Affiliations: 1
Identifiers
Doi:
10.1093/rheumatology/keh636
ISSN:
14620324
e-ISSN:
14620332
Research Areas
Infectious Diseases
Maternal And Child Health
Study Design
Cross Sectional Study
Cohort Study
Participants Gender
Male
Female