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agricultural and biological sciences

Out of Southern East Asia of the Brown Rat Revealed by Large-Scale Genome Sequencing

Molecular Biology and Evolution, Volume 35, No. 1, Year 2018

The geographic origin and migration of the brown rat (Rattus norvegicus) remain subjects of considerable debate. In this study, we sequenced whole genomes of 110 wild brown rats with a diverse world-wide representation. We reveal that brown rats migrated out of southern East Asia, rather than northern Asia as formerly suggested, into the Middle East and then to Europe and Africa, thousands of years ago. Comparison of genomes from different geographical populations reveals that many genes involved in the immune system experienced positive selection in the wild brown rat.

Zeng, Lin
1. China, Kunming Kunming Institute of Zoology Chinese Academy of Sciences
2. China, Beijing University of Chinese Academy of Sciences
Ming, Chen
1. China, Beijing Chinese Academy of Sciences
2. China, Beijing University of Chinese Academy of Sciences
Li, Yan
1. China, Kunming Kunming Institute of Zoology Chinese Academy of Sciences
2. China, Kunming Yunnan University
Su, Ling Yan
1. China, Beijing University of Chinese Academy of Sciences
2. China, Kunming Kunming Institute of Zoology Chinese Academy of Sciences
Su, Yan Hua
1. China, Kunming Yunnan Agricultural University
Otecko, Newton Otieno
1. China, Kunming Kunming Institute of Zoology Chinese Academy of Sciences
2. China, Beijing University of Chinese Academy of Sciences
3. China, Beijing Chinese Academy of Sciences
Dalecky, Ambroise
1. France, Montpellier Inrae's Occitanie-montpellier Centre
2. France, Marseille Ird Institut de Recherche Pour le Developpement
Donnellan, Stephen C.
1. Australia, Adelaide South Australian Museum
Aplin, Ken P.
1. United States, Washington, D.c. Smithsonian National Museum of Natural History
Liu, Xiao Hui
1. China, Beijing Chinese Academy of Agricultural Sciences
Song, Ying
1. China, Beijing Chinese Academy of Agricultural Sciences
Zhang, Zhibin
1. China, Beijing Institute of Zoology Chinese Academy of Sciences
Esmailizadeh, Ali K.
1. Iran, Kerman Daneshgahe Shahid Bahonar-e-kerman
Sohrabi, Saeed S.
1. Iran, Kerman Daneshgahe Shahid Bahonar-e-kerman
Nanaei, Hojjat Asadollahpour
1. Iran, Kerman Daneshgahe Shahid Bahonar-e-kerman
Liu, Hequn
1. China, Kunming Kunming Institute of Zoology Chinese Academy of Sciences
2. China, Beijing University of Chinese Academy of Sciences
Wang, Mingshan
1. China, Kunming Kunming Institute of Zoology Chinese Academy of Sciences
2. China, Beijing University of Chinese Academy of Sciences
Ag Atteynine, Solimane
1. Mali, Bamako Institut de Recherche Pour le Developpement Mali
2. Mali, Bamako Université Des Sciences
Rocamora, Gérard J.
1. Seychelles, Mahe University of Seychelles
Brescia, Fabrice
1. New Caledonia, Mont-dore Institut Agronomique Néo-calédonien
Morand, Serge
1. France, Paris Cnrs Centre National de la Recherche Scientifique
Irwin, David M.
1. China, Kunming Kunming Institute of Zoology Chinese Academy of Sciences
2. Canada, Toronto University of Toronto
Peng, Minsheng
1. China, Kunming Kunming Institute of Zoology Chinese Academy of Sciences
2. China, Beijing University of Chinese Academy of Sciences
3. China, Beijing Chinese Academy of Sciences
Yao, Yong Gang
1. China, Beijing University of Chinese Academy of Sciences
2. China, Kunming Kunming Institute of Zoology Chinese Academy of Sciences
Li, Hai Peng
1. China, Beijing Chinese Academy of Sciences
Wu, Dongdong
1. China, Kunming Kunming Institute of Zoology Chinese Academy of Sciences
2. China, Beijing University of Chinese Academy of Sciences
3. China, Beijing Chinese Academy of Sciences
Zhang, Yaping Pingi
1. China, Kunming Kunming Institute of Zoology Chinese Academy of Sciences
2. China, Beijing University of Chinese Academy of Sciences
3. China, Kunming Yunnan University

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Out of Southern East Asia of the Brown Rat Revealed by Large-Scale Genome Sequencing

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AFRICAN RESEARCH NEXUS

Out of Southern East Asia of the Brown Rat Revealed by Large-Scale Genome Sequencing

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