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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Etiology of acute lower respiratory tract infections in children in a rural community in the gambia
Pediatric Infectious Disease Journal, Volume 11, No. 6, Year 1992
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Description
Approximately 500 children younger than 5 years old resident in 7 villages in a rural area of the Gambia were monitored closely for 1 year for episodes of acute lower respiratory tract infection (ALRI). Each episode was investigated with antigen detection techniques and antibody assays as well as culture for bacteria and viruses. A pathogen was identified in 76 (34.2%) of 222 cases with clinical signs of ALRI and in 34 (42%) of the 81 cases who, in addition, had radiologic evidence of ALRI. Evidence of infection with a bacterial pathogen, most commonly Streptococcus pneumoniae or Haemophilus influenzae, was obtained in 32 (14.4%) cases with clinical signs of ALRI (23.5% of those with radiologically proved pneumonia). Viral agents were cultured from 42 (19%) of 221 cases but also from 14 (14.6%) of 96 controls some of whom had minor symptoms of upper respiratory tract infection. In the absence of an outbreak of respiratory syncytial virus the viral agents recovered most often were influenza A and adenoviruses. © 1992 by Williams and Wilkins.
Authors & Co-Authors
Forgie, Ian M.
Gambia, Banjul
Medical Council Laboratories
Campbell, Harry
Gambia, Banjul
Medical Council Laboratories
Lloyd-Evans, Nellie E.
Gambia
Mrc Joint Research Unit
Leinonen, Maija K.
Finland, Helsinki
Terveyden ja Hyvinvoinnin Laitos
O'neill, Kevin P.
Gambia, Banjul
Medical Council Laboratories
Saikku, Pekka
Finland, Helsinki
Terveyden ja Hyvinvoinnin Laitos
Finland, Helsinki
Helsingin Yliopisto
Whittle, Hilton C.
Gambia, Banjul
Medical Council Laboratories
Greenwood, Brian M.
Gambia, Banjul
Medical Council Laboratories
Statistics
Citations: 63
Authors: 8
Affiliations: 4
Identifiers
Doi:
10.1097/00006454-199206000-00009
ISSN:
08913668
e-ISSN:
15320987
Research Areas
Maternal And Child Health
Study Locations
Gambia