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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
general
A test of the chromosomal theory of ecotypic speciation in Anopheles gambiae
Proceedings of the National Academy of Sciences of the United States of America, Volume 105, No. 8, Year 2008
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Description
The role of chromosomal inversions in speciation has long been of interest to evolutionists. Recent quantitative modeling has stimulated reconsideration of previous conceptual models for chromosomal speciation. Anopheles gambiae, the most important vector of human malaria, carries abundant chromosomal inversion polymorphism nonrandomly associated with ecotypes that mate assortatively. Here, we consider the potential role of paracentric inversions in promoting speciation in A. gambiae via "ecotypification," a term that refers to differentiation arising from local adaptation. In particular, we focus on the Bamako form, an ecotype characterized by low inversion polymorphism and fixation of an inversion, 2Rj, that is very rare or absent in all other forms of A. gambiae. The Bamako form has a restricted distribution by the upper Niger River and its tributaries that is associated with a distinctive type of larval habitat, laterite rock pools, hypothesized to be its optimal breeding site. We first present computer simulations to investigate whether the population dynamics of A. gambiae are consistent with chromosomal speciation by ecotypification. The models are parameterized using field observations on the various forms of A. gambiae that exist in Mali, West Africa. We then report on the distribution of larvae of this species collected from rock pools and more characteristic breeding sites nearby. Both the simulations and field observations support the thesis that speciation by ecotypification is occurring, or has occurred, prompting consideration of Bamako as an independent species. © 2008 by The National Academy of Sciences of the USA.
Available Materials
https://efashare.b-cdn.net/share/pmc/articles/PMC2268564/bin/pnas_0709806105_index.html
https://efashare.b-cdn.net/share/pmc/articles/PMC2268564/bin/pnas_0709806105_2.pdf
https://efashare.b-cdn.net/share/pmc/articles/PMC2268564/bin/pnas_0709806105_1.pdf
Authors & Co-Authors
Manoukis, Nicholas C.
United States, Los Angeles
University of California, Los Angeles
United States, Bethesda
National Institute of Allergy and Infectious Diseases Niaid
Powell, Jeffrey Robert
United States, New Haven
Yale University
Touré, Mahamoudou B.
Mali, Bamako
University of Bamako
Sacko, Adama K.
Mali, Bamako
University of Bamako
Edillo, Frances E.
Philippines, Cebu
University of San Carlos
Coulibaly, Mamadou B.
Mali, Bamako
University of Bamako
United States, Notre Dame
University of Notre Dame
Traoré, Sékou Fantamady
Mali, Bamako
University of Bamako
Taylor, Charles E.
United States, Los Angeles
University of California, Los Angeles
Besansky, Nora J.
United States, Notre Dame
University of Notre Dame
Statistics
Citations: 87
Authors: 9
Affiliations: 6
Identifiers
Doi:
10.1073/pnas.0709806105
ISSN:
00278424
Research Areas
Infectious Diseases
Study Design
Cross Sectional Study
Study Approach
Quantitative
Study Locations
Multi-countries
Mali
Niger