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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Four million newborn deaths: Is the global research agenda evidence-based?
Early Human Development, Volume 84, No. 12, Year 2008
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Description
Four million neonates die each year. These deaths are mostly in low-income countries, but neonatal mortality and morbidity are also a priority burden in high-income countries. Epidemiological evidence suggests newborn research would prioritise the poorest families; birth and the first days of life; major causes particularly infections, preterm birth and asphyxia; and include preventive strategies as well as improved care. However research investment is not commensurate to burden, and there is a mismatch with current research priorities. South Asia and sub Saharan Africa, with 75% of the burden, expend around US$20 million per year on newborn research, a fraction of what is spent on a smaller proportion of health problem in rich countries. We propose a research pipeline of description, discovery, development of solutions and delivery of research with scale-up to reach the poorest families. Listing research options and applying quantitative scoring enables systematic, transparent research prioritisation. As well as a research pipeline, a "people pipeline" is required to generate research capacity in low-income countries. © 2008 Elsevier Ltd. All rights reserved.
Authors & Co-Authors
Lawn, Joy E.
South Africa, Tygerberg
South African Medical Research Council
Rudan, Igor
Croatia, Split
School of Medicine, University of Split
United Kingdom, Edinburgh
Edinburgh Medical School
Rubens, Craig
Unknown Affiliation
Statistics
Citations: 35
Authors: 3
Affiliations: 3
Identifiers
Doi:
10.1016/j.earlhumdev.2008.09.009
ISSN:
03783782
Research Areas
Maternal And Child Health
Study Approach
Quantitative