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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Evidence for stopping mass drug administration for lymphatic filariasis in some, but not all local government areas of Plateau and Nasarawa States, Nigeria
American Journal of Tropical Medicine and Hygiene, Volume 87, No. 2, Year 2012
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Description
An average of six annual rounds of ivermectin and albendazole were distributed in Plateau and Nasarawa States, Nigeria, to eliminate lymphatic filariasis. From 2007 to 2008, population-based surveys were implemented in all 30 local government areas (LGAs) of the two states to determine the prevalence of Wuchereria bancrofti antigenemia to assess which LGA mass drug administration (MDA) could be halted. In total, 36,681 persons from 7,819 households were examined for filarial antigen as determined by immunochromatographic card tests. Overall antigen prevalence was 3.05% (exact upper 95% confidence interval [CI] = 3.41%) with an upper 95% CI range by LGA of 0.50-19.3%. Among 3,233 children 6-7 years of age, overall antigen prevalence was 1.71% (exact upper 95% CI = 2.19%), too high to recommend generally halting MDA in the two-state area. However, based on criteria of < 2% antigenemia among persons > 2 years of age, stopping MDA was recommended for 10 LGAs. Copyright © 2012 by The American Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
King, Jonathan D.
United States, Atlanta
The Carter Center
Eigege, Abel
United States, Atlanta
The Carter Center
Umaru, John
United States, Atlanta
The Carter Center
Jip, Nimzing
United States, Atlanta
The Carter Center
Miri, Emmanuel S.
United States, Atlanta
The Carter Center
Jiya, Jonathan
Nigeria, Abuja
Federal Ministry of Health
Alphonsus, Kal
United States, Atlanta
The Carter Center
Sambo, Yohanna
United States, Atlanta
The Carter Center
Graves, Patricia M.
United States, Atlanta
The Carter Center
Richards, Frank O.
United States, Atlanta
The Carter Center
Statistics
Citations: 17
Authors: 10
Affiliations: 2
Identifiers
Doi:
10.4269/ajtmh.2012.11-0718
ISSN:
00029637
Research Areas
Health System And Policy
Maternal And Child Health
Study Design
Cross Sectional Study
Study Locations
Nigeria