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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Triglyceride lowering effect of MaxEPA fish lipid concentrate: A multicentre placebo controlled double blind study
Clinica Chimica Acta, Volume 178, No. 3, Year 1988
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Description
A multicentre, double blind, randomised between-group study comparing the triglyceride lowering effect of MaxEPA, a natural marine oil, and a placebo control is described. Eighty-six patients with hypertriglyceridaemia (fasting serum triglyceride ≥ 2 mmol/l) were studied for three months. There were no significant differences between the groups (48 active, 38 control) in respect of age, sex, height or weight, smoking habits or alcohol consumption. After one month triglyceride levels were reduced significantly from baseline in the treatment group and there was also a highly significant difference between the groups in favour of the marine oil. There was no significant change in serum total cholesterol in either group but there were fluctuations in high density lipoprotein (HDL) in both groups. Minor gastrointestinal side effects were reported by patients in both groups. Standard haematological and biochemical tests were done and there were no significant changes from baseline. © 1988.
Authors & Co-Authors
Miller, J. Paul
United Kingdom, Manchester
Manchester University Nhs Foundation Trust
Heath, I. D.
Canada, Halifax
Halifax General Hospital
Choraria, S. K.
United Kingdom, Coventry
Walsgrave Hospital
Shephard, N. W.
United Kingdom, Isleworth
West Middlesex University Hospital
Gajendragadkar, R. V.
Egypt
King Khalid Hospital
Harcus, A. W.
United Kingdom, Hull
Medicos Ltd.
Batson, G. A.
United Kingdom, Scunthorpe
Scunthorpe General Hospital
Smith, D. W.
United Kingdom, York
Huby
Saynor, R.
United Kingdom, Sheffield
Northern General Hospital
Statistics
Citations: 24
Authors: 9
Affiliations: 9
Identifiers
Doi:
10.1016/0009-8981(88)90233-1
ISSN:
00098981
Research Areas
Disability
Substance Abuse