Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Mobile phone technologies improve adherence to antiretroviral treatment in a resource-limited setting: A randomized controlled trial of text message reminders
AIDS, Volume 25, No. 6, Year 2011
Notification
URL copied to clipboard!
Description
OBJECTIVE: There is limited evidence on whether growing mobile phone availability in sub-Saharan Africa can be used to promote high adherence to antiretroviral therapy (ART). This study tested the efficacy of short message service (SMS) reminders on adherence to ART among patients attending a rural clinic in Kenya. DESIGN: A randomized controlled trial of four SMS reminder interventions with 48 weeks of follow-up. METHODS: Four hundred and thirty-one adult patients who had initiated ART within 3 months were enrolled and randomly assigned to a control group or one of the four intervention groups. Participants in the intervention groups received SMS reminders that were either short or long and sent at a daily or weekly frequency. Adherence was measured using the medication event monitoring system. The primary outcome was whether adherence exceeded 90% during each 12-week period of analysis and the 48-week study period. The secondary outcome was whether there were treatment interruptions lasting at least 48 h. RESULTS: In intention-to-treat analysis, 53% of participants receiving weekly SMS reminders achieved adherence of at least 90% during the 48 weeks of the study, compared with 40% of participants in the control group (P = 0.03). Participants in groups receiving weekly reminders were also significantly less likely to experience treatment interruptions exceeding 48 h during the 48-week follow-up period than participants in the control group (81 vs. 90%, P = 0.03). CONCLUSION: These results suggest that SMS reminders may be an important tool to achieve optimal treatment response in resource-limited settings. © 2011 Lippincott Williams & Wilkins, Inc.
Authors & Co-Authors
Pop-Eleches, Cristian
United States, New York
Columbia University
Thirumurthy, Harsha
United States, Chapel Hill
The University of North Carolina at Chapel Hill
United States, Washington, D.c.
Georgetown University
Habyarimana, James P.
United States, Washington, D.c.
Georgetown University
Zivin, Joshua G.
United States, La Jolla
School of Global Policy and Strategy
Goldstein, Markus
United States, Washington, D.c.
The World Bank, Usa
de Walque, Damien
United States, Washington, D.c.
The World Bank, Usa
MacKeen, Leslie
United States, Washington, D.c.
United States Agency for International Development
Haberer, Jessica Elizabeth
United States, Boston
Massachusetts General Hospital
Kimaiyo, Sylvester N.
Kenya, Eldoret
Moi University
Sidle, John E.
United States, Indianapolis
Indiana University School of Medicine
Kenya, Eldoret
Moi University
Ngare, Duncan K.
Kenya, Eldoret
Moi University
Bangsberg, David R.
United States, Cambridge
Massachusetts Institute of Technology
Uganda, Mbarara
Mbarara University of Science and Technology
Statistics
Citations: 930
Authors: 12
Affiliations: 11
Identifiers
Doi:
10.1097/QAD.0b013e32834380c1
e-ISSN:
14735571
Research Areas
Health System And Policy
Study Design
Randomised Control Trial
Cohort Study
Study Approach
Quantitative
Study Locations
Kenya