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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
DNA profiling of human blood in anophelines from lowland and highland sites in western Kenya
American Journal of Tropical Medicine and Hygiene, Volume 75, No. 2, Year 2006
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Description
We used polymerase chain reaction (PCR)-based DNA profiling to determine the person from whom Anopheles funestus and An. gambiae collected in natural human habitations obtained their blood meals. Less than 20% of human hosts contributed to > 50% of all blood meals, and 42% were not bitten at all, including people in the age group bitten most often. As expected, bites were unevenly distributed by age (young adults > older adults > children). Use of untreated bed nets by adults, but not children, seemed to redirect bites to children. Multiple blood meals in a single gonotrophic cycle occurred frequently enough to be epidemiologically important (14% for An. funestus and 11% for An. gambiae). Mosquitoes that did not bite a person who slept in the collection house can affect estimation of entomological risk. Mosquito-human interactions did not differ across ecologically and epidemiologically distinct highland and lowland sites. Copyright © 2006 by The American Society of Tropical Medicine and Hygiene.
Authors & Co-Authors
Scott, Thomas W.
United States, Davis
University of California, Davis
Githeko, Andrew K.
Kenya, Nairobi
Kenya Medical Research Institute
Fleisher, Andrew
United States, Davis
University of California, Davis
Harrington, Laura C.
United States, Ithaca
Cornell University
Yan, Guiyun Yun
United States, Buffalo
University at Buffalo, the State University of new York
Statistics
Citations: 49
Authors: 5
Affiliations: 4
Identifiers
Doi:
10.4269/ajtmh.2006.75.231
ISSN:
00029637
Research Areas
Genetics And Genomics
Health System And Policy
Maternal And Child Health
Study Locations
Kenya