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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Genetic diversity of longtail macaques (Macaca fascicularis) on the island of Mauritius: An assessment of nuclear and mitochondrial DNA polymorphisms
Journal of Medical Primatology, Volume 37, No. 1, Year 2008
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Description
Background: Individuals from an introduced population of longtail macaques on Mauritius have been extensively used in recent research. This population has low MHC gene diversity, and is thus regarded as a valuable resource for research. Methods: We investigated the genetic diversity of this population using multiple molecular markers located in mitochondrial DNA and microsatellite DNA loci on the autosomes and the Y chromosome. We tested samples from 82 individuals taken from seven study sites. Results and Conclusions: We found this population to be panmictic, with a low degree of genetic variability. On the basis of an mtDNA phylogeny, we inferred that these macaques' ancestors originated from Java in Asia. Weak gametic disequilibrium was observed, suggesting decay of non-random associations between genomic genes at the time of founding. The results suggest that macaques bred in Mauritius are valuable as model animals for biomedical research because of their genetic homogeneity. © 2007 The Authors Journal compilation 2007 Blackwell Munksgaard.
Authors & Co-Authors
Kawamoto, Yoshi
Japan, Kyoto
Kyoto University
Kawamoto, Sakie
Japan, Kyoto
Kyoto University
Matsubayashi, Kiyoaki
Japan, Kyoto
Kyoto University
Nozawa, Ken
Japan, Kyoto
Kyoto University
Watanabe, Tsuyoshi
Japan, Nagoya
Sugiyama Jogakuen University
Stanley, Marys Ann
Mauritius
Bioculture Mtius. Ltd
Perwitasari-Farajallah Dyah, D.
Indonesia, Bogor
Ipb University
Statistics
Citations: 48
Authors: 7
Affiliations: 4
Identifiers
Doi:
10.1111/j.1600-0684.2007.00225.x
ISSN:
00472565
e-ISSN:
16000684
Research Areas
Cancer
Genetics And Genomics
Study Design
Cross Sectional Study
Study Locations
Mauritius