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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
DDPC: Dragon database of genes associated with prostate cancer
Nucleic Acids Research, Volume 39, No. SUPPL. 1, Year 2011
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Description
Prostate cancer (PC) is one of the most commonly diagnosed cancers in men. PC is relatively difficult to diagnose due to a lack of clear early symptoms. Extensive research of PC has led to the availability of a large amount of data on PC. Several hundred genes are implicated in different stages of PC, which may help in developing diagnostic methods or even cures. In spite of this accumulated information, effective diagnostics and treatments remain evasive. We have developed Dragon Database of Genes associated with Prostate Cancer (DDPC) as an integrated knowledgebase of genes experimentally verified as implicated in PC. DDPC is distinctive from other databases in that (i) it provides pre-compiled biomedical text-mining information on PC, which otherwise require tedious computational analyses, (ii) it integrates data on molecular interactions, pathways, gene ontologies, gene regulation at molecular level, predicted transcription factor binding sites on promoters of PC implicated genes and transcription factors that correspond to these binding sites and (iii) it contains DrugBank data on drugs associated with PC. We believe this resource will serve as a source of useful information for research on PC. DDPC is freely accessible for academic and non-profit users via http://apps.sanbi.ac.za/ddpc/ and http://cbrc .kaust.edu.sa/ddpc/. © The Author(s) 2010.
Authors & Co-Authors
Maqungo, Monique
South Africa, Bellville
University of the Western Cape
Kaur, Mandeep
Saudi Arabia, Thuwal
King Abdullah University of Science and Technology
Kwofie, Samuel Kojo
South Africa, Bellville
University of the Western Cape
Radovanovic, Aleksandar
Saudi Arabia, Thuwal
King Abdullah University of Science and Technology
Schaefer, Ulf
Saudi Arabia, Thuwal
King Abdullah University of Science and Technology
Schmeier, Sebastian
Saudi Arabia, Thuwal
King Abdullah University of Science and Technology
Oppon, Ekow
South Africa, Bellville
University of the Western Cape
Christoffels, Alan G.
South Africa, Bellville
University of the Western Cape
Bajic, Vladimir B.
Saudi Arabia, Thuwal
King Abdullah University of Science and Technology
Statistics
Citations: 46
Authors: 9
Affiliations: 2
Identifiers
Doi:
10.1093/nar/gkq849
ISSN:
03051048
e-ISSN:
13624962
Research Areas
Cancer
Environmental
Genetics And Genomics
Participants Gender
Male