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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
The effectiveness of Hibiscus sabdariffa in the treatment of hypertension: A systematic review
Phytomedicine, Volume 17, No. 2, Year 2010
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Description
Introduction: Hypertension is a common global health problem with significant mortality and morbidity. Hibiscus sabdariffa is a plant known in many countries and is consumed as hot and cold drinks In addition to its use in folk medicine; it has been suggested as treatment for many conditions including hypertension. Objectives: The objectives of this review were to examine the evidence of effectiveness and safety of hibiscus in the treatment of hypertension. Methods: We searched several medical databases (MEDLINE, EMBASE, CINAHL, Cochrane Central Register of Controlled Trials, and the specialized register of the Cochrane Hypertension Group and the general engine Google) to January 2009. We included randomized controlled trials that had examined Hibiscus's effectiveness and safety in the treatment of primary hypertension in adults. Two authors independently selected the trials for the review, extracted the data, and critically appraised the included studies. Results: Four trials, with a total of 390 patients, met our inclusion criteria. Two studies compared Hibiscus sabdariffa to black tea; one study compared it to captopril and one to lisinopril. The studies found that Hibiscus had greater blood pressure reduction than tea but less than the ACE-inhibitors. However, all studies, except one, were short term and of poor quality with a Jadad scoring of <3 and did not meet international standards. Conclusion: The four randomized controlled studies identified in this review do not provide reliable evidence to support recommending Hibiscus sabdariffa for the treatment of primary hypertension in adults. © 2009 Elsevier GmbH.
Authors & Co-Authors
Wahabi, Hayfaa Abdulmajeed
Saudi Arabia, Riyadh
College of Medicine
Alansary, L. A.
Saudi Arabia, Riyadh
College of Medicine
Al-Sabban, A. H.
Saudi Arabia, Riyadh
College of Medicine
Glasziuo, P.
Saudi Arabia, Riyadh
College of Medicine
United Kingdom, Oxford
University of Oxford Medical Sciences Division
Statistics
Citations: 96
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.1016/j.phymed.2009.09.002
ISSN:
09447113
Research Areas
Health System And Policy
Noncommunicable Diseases
Study Approach
Systematic review