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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Idiopathic granulomatous mastitis: A report of twenty cases
Diagnostic and Interventional Imaging, Volume 93, No. 7-8, Year 2012
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Description
Introduction: Idiopathic granulomatous mastitis is a benign lesion of the mammary gland characterised by the presence of non-infectious inflammatory breast lesions limited to the lobules. Objective: We report twenty cases of idiopathic granulomatous mastitis (IGM) with a discussion of epidemiology, clinical and diagnostic features, treatment and progress of this pathological entity. Materials and methods: A retrospective study of twenty cases compiled from a ten-year period, from 952 pathological anatomy examinations carried out to investigate various breast pathologies. Results: The patients had a mean age of 45.5 years. Clinical examinations revealed a tumefaction measuring between 2.5 and 18 cm in diameter. The mean size was 5.5 cm. Mammography showed nodular lesions and sonography demonstrated hypoechoic nodules. On histological examination there was a granulomatous inflammatory infiltrate of epithelioid and giant cells, without caseation necrosis, made up of lymphocytes, plasma cells and neutrophils. Microbiology investigations were negative. Lesion involvement was principally lobulocentric. Surgical excision of the lesions was combined with corticosteroid therapy in twelve cases, with non-steroidal anti-inflammatory drugs in another four and with antibiotic therapy in four cases. The patients made good progress in the short-term. Discussion and conclusion: IGM is a rare entity. It poses a problem of differential diagnosis because it clinically resembles other forms of mastitis. The diagnosis can be made with certainty on histological studies. The treatment is medical alongside surgical excision. The prognosis of this disease remains favourable. © 2012 Éditions françaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.
Authors & Co-Authors
Boufettal, Houssine
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Essodegui, Fatiha
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Noun, Mohammed
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Hermas, Saïd
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Samouh, Naïma
Morocco, Casablanca
Centre Hospitalier Universitaire Ibn Rochd
Statistics
Citations: 53
Authors: 5
Affiliations: 1
Identifiers
Doi:
10.1016/j.diii.2012.04.028
ISSN:
22115684
e-ISSN:
22115684
Research Areas
Cancer
Health System And Policy
Study Design
Cohort Study