Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Evidence of chromosomal instability in neurofibromatosis
Cancer, Volume 55, No. 10, Year 1985
Notification
URL copied to clipboard!
Description
Blood lymphocytes from six unrelated patients with neurofibromatosis and three normal controls were examined for their response to different doses (0, 75, 150, 300, 400 rad) of x‐radiation, as measured by chromosome aberrations (gaps, breaks, dicentrics, centric rings, acentric ring, fragments, and minutes). Cytogenetic studies on phytohemagglutinin‐stimulated cells revealed chromosomal instability in the neurofibromatosis lymphocytes as shown by the significant increase in the incidence of gaps, breaks and dicentrics. This increase paralleled the increase in the dose of irradiation. The significance of these findings is discussed. Copyright © 1985 American Cancer Society
Authors & Co-Authors
Hafez, Mohamed M.
Egypt, Mansoura
Faculty of Medicine
Sharaf, Layla
Egypt, Mansoura
Faculty of Medicine
El‐Nabi, Samya M.Abd
Egypt, Mansoura
Faculty of Medicine
Al-Wehedy, Adel
Egypt, Mansoura
Faculty of Medicine
Statistics
Citations: 28
Authors: 4
Affiliations: 1
Identifiers
Doi:
10.1002/1097-0142(19850515)55:10<2434::AID-CNCR2820551022>3.0.CO;2-A
ISSN:
0008543X
e-ISSN:
10970142
Research Areas
Cancer
Study Design
Cohort Study