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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Pemphigus Foliaceus in Young Women: An Endemic Focus in the Sousse Area of Tunisia
Archives of Dermatology, Volume 129, No. 1, Year 1993
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Description
Background and Design.—With the exception of some areas in Brazil, pemphigus is an exceptional disease. Several previous observations suggested that pemphigus foliaceus occurred more frequently than expected in Tunisia. To confirm these observations, a 15-month prospective survey was undertaken at the University Hospital of Sousse in Tunisia. Results.—During the survey, 23 patients with pemphigus were observed. Twenty of 23 cases were of pemphigus foliaceus that affected only young women. Seven patients had the clinical features of pemphigus herpetiformis. The estimated incidence of pemphigus foliaceus in the Sousse area was four new cases per million inhabitants per year, far above European or North American incidence but lower than the incidence in the most severely affected areas in Brazil. The high prevalence of the herpetiform clinical variant, the young age, the feminine exclusivity, and the absence of familial cases differentiated this Tunisian pemphigus both from pemphigus foliaceus observed in Europe and North America and from the Brazilian fogo selvagem. No etiologic factor was identified. Conclusions.—This study suggests the existence in Tunisia (and possibly in all North Africa) of an endemic form of pemphigus foliaceus restricted to young women. © 1993, American Medical Association. All rights reserved.
Authors & Co-Authors
Morini, Jean Pierre
France, Creteil
Hôpital Henri Mondor
Jomaa, Bechir
Tunisia
Hospital of Sousse
Gorgi, Yosrl
Tunisia, Tunis
Faculté de Médecine de Tunis
Saguem, Mohamed H.
Tunisia
Anatomical-pathology Laboratory of Sousse
Nouira, Rafiâa B.
Tunisia
Hospital of Sousse
Roujeau, Jean Claude
France, Creteil
Hôpital Henri Mondor
Revuz, Jean E.
France, Creteil
Hôpital Henri Mondor
Statistics
Citations: 79
Authors: 7
Affiliations: 4
Identifiers
Doi:
10.1001/archderm.1993.01680220081019
ISSN:
0003987X
e-ISSN:
15383652
Research Areas
Health System And Policy
Study Design
Cross Sectional Study
Cohort Study
Study Approach
Quantitative
Study Locations
Multi-countries
Tunisia
Participants Gender
Female