Ceruloplasmin serum concentrations in a large randomized population sample; [Serumcoeruloplasmin in einer randomisierten bevölkerungsstichprobe mit 2 445 probanden]

The relevance of low ceruloplasmin serum concentrations for the differential diagnosis in neurology and psychiatry rests upon the association with neurodegenerative disorders with brain iron accumulation, on the one hand, and Wilson disease, on the other hand. The present study reports immunonephelometrical measurements of ceruloplasmin serum concentrations in a large randomized population sample. Results are in accordance with published data and show dependency on markers of inflammation, gender and history of oral contraception; in addition, a strong correlation to serum cholesterol fractions is being demonstrated. It would appear useful to account for these when evaluating ceruloplasmin serum concentrations. © Schattauer 2011.