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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
A novel family of hemicellulolytic α-glucuronidase
FEBS Letters, Volume 583, No. 9, Year 2009
Notification
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Description
Investigation of the xylanolytic enzyme system of the xylose-fermenting yeast Pichia stipitis resulted in the discovery of an extracellular α-glucuronidase efficiently debranching hardwood glucuronoxylan. This activity is not exhibited by more extensively investigated α-glucuronidases of glycoside hydrolase (GH) family 67, operating on substrates in which the uronic acid is linked to the non-reducing xylopyranosyl residues of main chain fragments. The N-terminus of the purified enzyme corresponded exactly to the P. stipitis gene ABN67901 coding for a protein of unknown function. BLAST search revealed the presence of similar genes in genomes of other microorganisms. These results lead to the emergence of a new family of α-glucuronidases. © 2009 Federation of European Biochemical Societies.
Authors & Co-Authors
Ryabova, Olena
Slovakia, Bratislava
Slovak Academy of Sciences
Vršanská, Mária
Slovakia, Bratislava
Slovak Academy of Sciences
Kaneko, Satoshi
Japan, Tsukuba
Food Research Institute, Naro
van Zyl, W. H.
South Africa, Stellenbosch
Stellenbosch University
Biely, Peter
Slovakia, Bratislava
Slovak Academy of Sciences
Statistics
Citations: 79
Authors: 5
Affiliations: 3
Identifiers
Doi:
10.1016/j.febslet.2009.03.057
ISSN:
00145793
Research Areas
Genetics And Genomics