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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Abdominal ultrasonography in HIV/AIDS patients in southwestern Nigeria
BMC Medical Imaging, Volume 8, Article 5, Year 2008
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Description
Background: Though the major target of the HIV-virus is the immune system, the frequency of abdominal disorders in HIV/AIDS patients has been reported to be second only to pulmonary disease. These abdominal manifestations may be on the increase as the use of antiretroviral therapy has increased life expectancy and improved quality of life. Ultrasonography is an easy to perform, non invasive, inexpensive and safe imaging technique that is invaluable in Africa where AIDS is most prevalent and where sophisticated diagnostic tools are not readily available. Purpose: To describe the findings and evaluate the clinical utility of abdominal ultrasonography in HIV/AIDS patients in Ibadan, Nigeria Methods: A Prospective evaluation of the abdominal ultrasonography of 391 HIV-positive patients as well as 391 age and sex-matched HIV-negative patients were carried out at the University College Hospital, Ibadan. Results: Of the 391 cases studied, 260 (66.5%) were females; the mean age was 38.02 years, (range 15-66 years). The disease was most prevalent in the 4th decade with an incidence of 40.4%. Compared with the HIV-negative individuals, the HIV+ group of patients had a significantly higher proportion of splenomegaly (13.5% vs. 7.7%; p < 0.01), lymphadenopathy (2.0% vs. 1.3%; p < 0.70), and renal abnormalities (8.4% vs. 3.8%; p < 0.02). There were no differences in hepatic and pancreatic abnormalities between the HIV+ and HIV- groups. There were significantly fewer gallstones in the HIV+ group (1.4% vs. 5.1%; p < 0.01). Conclusion: AIDS is a multi-systemic disease and its demographic and clinical pattern remains the same globally. Ultrasonography is optimally suited for its clinical management especially in Africa. Its accuracy and sensitivity may be much improved with clinico-pathologic correlation which may not be readily available in developing countries; further studies may provide this much needed diagnostic algorithms. © 2008 Obajimi et al; licensee BioMed Central Ltd.
Authors & Co-Authors
Obajimi, Millicent Olubunmi
Nigeria, Ibadan
University College Hospital, Ibadan
Atalabi, Mojisola O.
Nigeria, Ibadan
University College Hospital, Ibadan
Ogbole, G. I.
Nigeria, Ibadan
University College Hospital, Ibadan
Adeniji-Sofoluwe, Adenike Temitayo
Nigeria, Ibadan
University College Hospital, Ibadan
Agunloye, Atinuke M.
Nigeria, Ibadan
University College Hospital, Ibadan
Adekanmi, A. J.
Nigeria, Ibadan
University College Hospital, Ibadan
Osuagwu, Yvonne U.
Nigeria, Ibadan
University College Hospital, Ibadan
Olarinoye-Akorede, S. A.
Nigeria, Ibadan
University College Hospital, Ibadan
Olusola-Bello, Mojisola Adejoke
Nigeria, Ibadan
University College Hospital, Ibadan
Ogunseyinde, Ayotunde Oluremi
Nigeria, Ibadan
University College Hospital, Ibadan
Aken'Ova, Yetunde A.
Nigeria, Ibadan
University College Hospital, Ibadan
Adewole, Isaac Folorunso A.
Nigeria, Ibadan
University College Hospital, Ibadan
Statistics
Citations: 35
Authors: 12
Affiliations: 1
Identifiers
Doi:
10.1186/1471-2342-8-5
e-ISSN:
14712342
Research Areas
Disability
Health System And Policy
Infectious Diseases
Study Design
Cohort Study
Study Locations
Nigeria
Participants Gender
Female