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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Prevalence of HIV among women entering labor who accepted or declined voluntary counseling and testing
International Journal of Gynecology and Obstetrics, Volume 120, No. 2, Year 2013
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Description
Objective: To assess whether there was a difference in HIV seroprevalence between eligible women who declined and those who agreed to participate in a study of voluntary counseling and testing among women entering labor with unknown HIV status in South Africa. Methods: Anonymous cord blood specimens were collected - as dried blood spots - from all women approached for participation in a cluster-randomized trial. No patient identifiers were included on the cord blood specimens. The dried blood spots were analyzed for HIV antibody via enzyme immunoassay and western blotting. Results: Of 7238 women screened for study participation, 1041 (14.4%) had undocumented HIV status; of these women, 542 were eligible for inclusion and 343 enrolled. Based on 513 evaluable samples, the overall seroprevalence was 13.3% (95% confidence interval [CI], 10.4-16.5), which was similar to the 13.1% (95% CI, 9.7-17.2) seroprevalence among the 343 enrolled women. Conclusion: Seroprevalence among eligible women was similar to that among enrolled women, which indicates that study participation did not select for a group with an HIV seroprevalence substantially different from that among women who declined to enroll. © 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
Authors & Co-Authors
Theron, Gerhard Barnard
South Africa, Tygerberg
Tygerberg Hospital
Cababasay, Mae P.
United States, Boston
Center for Biostatistics in Aids Research
van Dyke, Russell B.
United States, New Orleans
Tulane University Health Sciences Center
Shapiro, David E.
United States, Boston
Center for Biostatistics in Aids Research
Louw, Jeanne
South Africa, Tygerberg
Tygerberg Hospital
Watts, Diane Heather
United States, Bethesda
National Institute of Child Health and Human Development Nichd
Bulterys, Marc G.
United States, Atlanta
Centers for Disease Control and Prevention
Styer, Linda M.
United States, Albany
Wadsworth Center for Laboratories and Research
Maupin, Robert T.
United States, New Orleans
Louisiana State University
Statistics
Citations: 9
Authors: 9
Affiliations: 7
Identifiers
Doi:
10.1016/j.ijgo.2012.07.029
ISSN:
00207292
e-ISSN:
18793479
Research Areas
Health System And Policy
Infectious Diseases
Study Design
Randomised Control Trial
Cross Sectional Study
Study Locations
South Africa
Participants Gender
Female