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medicine

Age dependence of adenovirus-specific neutralizing antibody titers in individuals from sub-Saharan Africa

Journal of Clinical Microbiology, Volume 44, No. 10, Year 2006

We assessed neutralizing antibody titers to adenovirus serotype 5 (Ad5) and six rare adenovirus serotypes, serotypes 11, 35, 50, 26, 48, and 49, in pediatric populations in sub-Saharan Africa. We observed a clear age dependence of Ad5-specific neutralizing antibody titers. These data will help to guide the development of Ad vector-based vaccines for human immunodeficiency virus type 1 and other pathogens. Copyright © 2006, American Society for Microbiology. All Rights Reserved.

Statistics
Citations: 117
Authors: 18
Affiliations: 6
Identifiers
Doi: 10.1128/JCM.01249-06
ISSN: 00951137

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