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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Adverse reactions after the use of sulphur hexafluoride (SonoVue) echo contrast agent
Journal of Cardiovascular Medicine, Volume 10, No. 1, Year 2009
Notification
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Description
The aim of the present study was to analyse the adverse effects of SonoVue echo contrast in a consecutive series of 352 cardiac patients during a 4-year period. During 352 consecutive cardiac SonoVue studies, seven patients (2.0%) experienced adverse effects. Four patients (1.1%) had mild allergic reactions causing skin erythema and mild sinus tachycardia, and three patients (0.9%) experienced a severe allergic reaction resulting in (nonfatal) shock. The reported incidence of adverse effects of SonoVue echo contrast in this consecutive series of cardiac patients seems markedly higher than those reported in a company postmarketing analysis. © 2009 Italian Federation of Cardiology.
Authors & Co-Authors
Geleijnse, Marcel L.
Netherlands, Rotterdam
Erasmus Mc
Nemes, Attila
Netherlands, Rotterdam
Erasmus Mc
Vletter, Wim B.
Netherlands, Rotterdam
Erasmus Mc
Michels, Michelle
Netherlands, Rotterdam
Erasmus Mc
Soliman, O. I.I.
Netherlands, Rotterdam
Erasmus Mc
Caliskan, Kadir C.
Netherlands, Rotterdam
Erasmus Mc
Galema, Tjebbe W.
Netherlands, Rotterdam
Erasmus Mc
Ten Cate, Folkert J.
Netherlands, Rotterdam
Erasmus Mc
Statistics
Citations: 45
Authors: 8
Affiliations: 1
Identifiers
Doi:
10.2459/JCM.0b013e328319bfba
ISSN:
15582027
Research Areas
Noncommunicable Diseases
Study Design
Cohort Study