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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Identification of measles virus genotypes from recent outbreaks in countries from the Eastern Mediterranean Region
Journal of Clinical Virology, Volume 34, No. 1, Year 2005
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Description
Background: Molecular characterization of measles viruses (MV) helps to identify transmission pathways of the virus and to document persistence or interruption of endemic virus circulation. In the Eastern Mediterranean Region, measles genotypes from only few countries have been documented. Objectives: This study reports the genetic characteristics of virus strains from recent measles outbreaks in Tunisia, Libya, Syria and Iran in 2002-2003. Study design: Virus sequences in the nucleoprotein gene were obtained by PCR amplification of virus isolates or serum samples. The sequences were compared to the reference ones for genotype identification and to other published sequences within the same genotype. Results and conclusions: The Tunisian and Libyan epidemic strains belonged to genotype B3, they were closely related to each other and to isolates from Western Africa. The Syrian and Iranian viruses belonged to genotype D4, and differed from each other and from the other published sequences within this genotype. Our results provide valuable baseline and new tools for improved virological measles surveillance in the future, at country, regional and global levels. © 2005 Elsevier B.V. All rights reserved.
Authors & Co-Authors
Djebbi, Ahlem
Tunisia, Tunis
Institut Pasteur de Tunis
Bahri, Olfa
Tunisia, Tunis
Institut Pasteur de Tunis
Mokhatri-Azad, Talat
Iran
National Laboratory for Measles
Alkhatib, Mouna
Syrian Arab Republic
National Laboratory for Measles
Ben-Yahia, Ahlem
Tunisia, Tunis
Institut Pasteur de Tunis
Rezig, Dorra
Tunisia, Tunis
Institut Pasteur de Tunis
Mohsni, Ezzeddine
Switzerland, Geneva
Organisation Mondiale de la Santé
Triki, Henda
Tunisia, Tunis
Institut Pasteur de Tunis
Statistics
Citations: 35
Authors: 8
Affiliations: 4
Identifiers
Doi:
10.1016/j.jcv.2004.11.026
ISSN:
13866532
Research Areas
Genetics And Genomics
Infectious Diseases
Study Locations
Libya
Tunisia