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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Cost-effectiveness of treatment strategies for cervical infection among women at high risk in Madagascar
Sexually Transmitted Diseases, Volume 34, No. 9, Year 2007
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Description
BACKGROUND: According to the national guidelines developed in 2001, a woman at high risk of gonorrhea and chlamydia in Madagascar is treated presumptively at her first sexually transmitted infection clinic visit; risk-based treatment (RB) is subsequently used at 3-month visits. OBJECTIVES: To compare health and economic outcomes for a 2-stage Markov process with the following 3 cervical infection treatment policies at baseline and at 3-month follow-up visit: presumptive treatment (PT), RB, and an interim laboratory/risk-based policy. STUDY DESIGN: Cost-effectiveness analysis was used to compare the 9 treatment strategies. RESULTS: When 3-month incidence of cervical infection is <20%, the national guidelines are less costly and less effective than both RB followed by PT, and PT at both visits. CONCLUSIONS: The national guidelines are a reasonable strategy, especially in the context of resource constraints, relatively low reinfection rates, and local preferences. © Copyright 2007 American Sexually Transmitted Diseases Association.
Authors & Co-Authors
McClamroch, Kristi J.
United States, Rensselaer
School of Public Health
Behets, Frieda M.T.F.
United States, Chapel Hill
The University of North Carolina at Chapel Hill
van Damme, Kathleen
United States, Chapel Hill
The University of North Carolina at Chapel Hill
Rabenja, Lovaniaina Ny
Madagascar, Antananarivo
Unc-mad
Myers, Evan
United States, Durham
Duke University School of Medicine
Statistics
Citations: 8
Authors: 5
Affiliations: 4
Identifiers
Doi:
10.1097/01.olq.0000258107.75888.0e
ISSN:
01485717
Research Areas
Health System And Policy
Sexual And Reproductive Health
Study Design
Cohort Study
Study Locations
Madagascar
Participants Gender
Female