Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Vaccine value profile for norovirus
Vaccine, Volume 41, Year 2023
Notification
URL copied to clipboard!
Description
Norovirus is attributed to nearly 1 out of every 5 episodes of diarrheal disease globally and is estimated to cause approximately 200,000 deaths annually worldwide, with 70,000 or more among children in developing countries. Noroviruses remain a leading cause of sporadic disease and outbreaks of acute gastroenteritis even in industrialized settings, highlighting that improved hygiene and sanitation alone may not be fully effective in controlling norovirus. Strengths in global progress towards a Norovirus vaccine include a diverse though not deep pipeline which includes multiple approaches, including some with proven technology platforms (e.g., VLP-based HPV vaccines). However, several gaps in knowledge persist, including a fulsome mechanistic understanding of how the virus attaches to human host cells, internalizes, and induces disease. © 2023 The Author(s)
Authors & Co-Authors
Armah, George Enyimah
Ghana, Accra
University of Ghana
Lopman, Benjamin Alan
United States, Atlanta
Emory University
Vinjé, Jan
United States, Atlanta
Centers for Disease Control and Prevention
O'Ryan, Miguel L.
Chile, Santiago
Universidad de Chile
Lanata, Claudio Franco
Peru, Lima
Instituto de Investigacion Nutricional
Groome, Michelle J.
South Africa, Johannesburg
University of the Witwatersrand
Riddle, Mark S.
United States, Reno
University of Nevada, Reno
Statistics
Authors: 7
Affiliations: 8
Identifiers
Doi:
10.1016/j.vaccine.2023.03.034
ISSN:
0264410X
Research Areas
Cancer
Environmental
Infectious Diseases
Maternal And Child Health