Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Homozygotes for the hereditary persistence of fetal hemoglobin: The ratio of
G
γ to
A
γ chains and biosynthetic studies
Biochemical Genetics, Volume 15, No. 11-12, Year 1977
Notification
URL copied to clipboard!
Description
Two sons of a previously reported Ghanaian homozygote for the hereditary persistence of fetal hemoglobin (HPFH) (Ringelhann et al., 1970) also are HPFH homozygotes. In addition, another unrelated adult Ghanaian homozygote has been detected. All of these Ghanaian homozygotes as well as three American Black HPFH homozygotes have the GγAγ type of HPFH with a Gγ to Aγ ratio of about 3:2, in contrast to an Asiatic Indian homozygote who has the Gγ type. Globin chain synthesis in HPFH homozygotes is unbalanced, with a γ/α ratio of 0.6 or less, whereas it is balanced in heterozygotes according to most reports. © 1977 Plenum Publishing Corporation.
Authors & Co-Authors
Ringelhann, Béla
Hungary, Budapest
Orfi
Acquaye, Clemenceau
Ghana, Kumasi
Kwame Nkrumah University of Science & Technology
Oldham, J. H.
Ghana, Kumasi
Kwame Nkrumah University of Science & Technology
Konotey-Ahulu, Felix I.D.
Ghana, Accra
Korle bu Teaching Hospital
Yawson, G.
Ghana, Accra
Atomic Energy Commission
Sukumaran, P. K.
India, Mumbai
Tata Memorial Hospital
Schroeder, W. A.
United States, Pasadena
California Institute of Technology
Huisman, Titus Hendrik Jan
United States, Augusta
Medical College of Georgia
Statistics
Citations: 8
Authors: 8
Affiliations: 7
Identifiers
Doi:
10.1007/BF00484499
ISSN:
00062928
e-ISSN:
15734927