Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Vaginal progesterone gel for luteal phase support in IVF/ICSI cycles: A meta-analysis
Fertility and Sterility, Volume 94, No. 6, Year 2010
Notification
URL copied to clipboard!
Description
Objective: To investigate whether vaginal progesterone gel may result in similar or higher pregnancy rates compared with all other vaginal progesterone forms when used for luteal-phase support. Design: Meta-analysis of randomized controlled trials using odds ratios (OR) and 95% confidence intervals (CI). Patient(s): Infertile women undergoing IVF or ICSI. Intervention(s): Vaginal progesterone gel 90mg once or twice daily versus any other vaginal progesterone form for luteal phase support. Main Outcome Measure(s): Clinical pregnancy rates. Result(s): Seven randomized controlled trials, involving 2,447 patients, were included in the analysis. No difference was observed in the overall clinical pregnancy rate when comparing vaginal progesterone gel with any other vaginal progesterone form. Moreover, clinical pregnancy rates were similar in protocols using only GnRH agonists and when comparing vaginal gel with the traditional treatment of 200 mg × 3 vaginal progesterone capsules. Conclusion(s): This meta-analysis provides solid evidence that no significant difference exists between vaginal gel and all other vaginal progesterone forms in terms of clinical pregnancy rates. Copyright © 2010 American Society for Reproductive Medicine, Published by Elsevier Inc.
Authors & Co-Authors
Polyzos, Nikolaos P.
Greece, Larissa
University Hospital of Larissa
Greece, Athens
Panhellenic Association for Continual Medical Research
Messini, Christina I.
Greece, Larissa
University Hospital of Larissa
Papanikolaou, Evangelos G.
Greece, Thessaloniki
Biogenesis
Mauri, Davide
Greece, Athens
Panhellenic Association for Continual Medical Research
Tzioras, Spyridon
Greece, Athens
Panhellenic Association for Continual Medical Research
Badawy, Ahmed Mahmoud Moustafa
Egypt, Mansoura
Faculty of Medicine
Messinis, Ioannis E.
Greece, Larissa
University Hospital of Larissa
Statistics
Citations: 29
Authors: 7
Affiliations: 4
Identifiers
Doi:
10.1016/j.fertnstert.2009.12.058
ISSN:
00150282
Research Areas
Health System And Policy
Maternal And Child Health
Sexual And Reproductive Health
Study Design
Randomised Control Trial
Study Approach
Systematic review
Participants Gender
Female