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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
Residual risk of transmission of HIV and HCV, in Senegalese national blood bank from 2003 to 2005
Transfusion Clinique et Biologique, Volume 16, No. 5-6, Year 2009
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Description
Background and aim: Using of safety blood products did not stop improving these last years. The use of effective methods as well immunologicals as virologicals ones really reduces risk associated to blood transfusion. However, it persists residual risk (RR) of transfusion transmitted viral diseases. The aim of our study was to detect cases of seroconversion for HIV,and HBV among donors in the Senegalese national blood bank. And then, we estimated the RR of these virus. Methods: We led a transverse retrospective study from 2003 (January 1st) to 2005 (December 31st). Had been included donors with at least two donations of blood during the period of study. They had to be seronegative for HIV and HBV after the first donation. All donors with only one donation had been excluded. RR was estimated by multiplying incidence rates by the durations of the window periods. Results: During 3 years, we collected 425,503 donations; 388 were positive for HIV and 4240 for HBV. But we noted only two cases of seroconversion for HIV and 23 for HBV. So, RR estimated was 3,5 in 100,000 donation for HIV and 102,45 in 100,000 donations for VHB. Conclusion: It emerges from this study that the risk of blood transmitted virus is always high. Introduction of more sensitive tests (as nucleic acid testing) would allow us to deliver more safety products. © 2009.
Authors & Co-Authors
Touré-Fall, Awa Oumar
Senegal, Dakar
Centre Hospitalier Universitaire Aristide le Dantec de Dakar
Senegal, Dakar
Université Cheikh Anta Diop de Dakar
Diéye, Tandakha Ndiaye D.
Senegal, Dakar
Université Cheikh Anta Diop de Dakar
Senegal, Dakar
Centre National de Transfusion Sanguine
Sall, Abibatou F.
Senegal, Dakar
Centre Hospitalier Universitaire Aristide le Dantec de Dakar
Senegal, Dakar
Université Cheikh Anta Diop de Dakar
Diop, Mamadou B.
Senegal, Dakar
Centre Hospitalier Universitaire Aristide le Dantec de Dakar
Senegal, Dakar
Centre National de Transfusion Sanguine
Seck, Moussa T.
Senegal, Dakar
Université Cheikh Anta Diop de Dakar
Senegal, Dakar
Centre National de Transfusion Sanguine
Diop, Saliou N.
Senegal, Dakar
Université Cheikh Anta Diop de Dakar
Senegal, Dakar
Centre National de Transfusion Sanguine
Thiam, Doudou
Senegal, Dakar
Centre Hospitalier Universitaire Aristide le Dantec de Dakar
Senegal, Dakar
Université Cheikh Anta Diop de Dakar
Senegal, Dakar
Centre National de Transfusion Sanguine
Diakhaté, Lamine
Senegal, Dakar
Université Cheikh Anta Diop de Dakar
Senegal, Dakar
Centre National de Transfusion Sanguine
Statistics
Citations: 25
Authors: 8
Affiliations: 3
Identifiers
Doi:
10.1016/j.tracli.2009.09.005
Research Areas
Infectious Diseases
Study Design
Cohort Study