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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
immunology and microbiology
Worldwide time trends for symptoms of rhinitis and conjunctivitis: Phase III of the International Study of Asthma and Allergies in Childhood
Pediatric Allergy and Immunology, Volume 19, No. 2, Year 2008
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Description
In Phase III of the International Study of Asthma and Allergies in Childhood (ISAAC) time trends in the prevalence of rhinoconjunctivitis symptoms were analysed. Cross-sectional questionnaire surveys with identical protocols and questionnaires were completed a mean of 7 yr apart in two age groups comprising 498,083 children. In the 13- to 14-yr age group 106 centres in 56 countries participated, and in the 6- to 7-yr age group 66 centres in 37 countries participated. A slight worldwide increase in rhinoconjunctivitis prevalence was observed, but the variations were large among the centres and there was no consistent regional pattern. Prevalence increases in the older children exceeding 1% per year were recorded in 13 centres, including 3 of 9 centres in Africa, 2 of 15 in Asia-Pacific, 1 of 8 in India, 3 of 15 in Latin America, 3 of 9 in Eastern Europe and 1 of 34 in Western and Northern Europe. Decreasing rhinoconjunctivititis prevalence of similar magnitude was only seen in four centres. The changes were less pronounced in the 6- to 7-yr-old children and only in one centre did any change exceed 1% per year. The decrease in highest prevalence rates in ISAAC Phase I suggests that the prevalence has peaked in those regions. An increase was recorded in several centres, mostly in low and mid-income countries. The increases were more pronounced in the older age group, suggesting that environmental influences on the development of allergy may not be limited to early childhood. © 2007 The Authors.
Authors & Co-Authors
Bjõrkstén, Bengt
Sweden, Stockholm
Karolinska Institutet
Clayton, Tadd Oliver
New Zealand, Auckland
The University of Auckland
Ellwood, Philippa Ellen
New Zealand, Auckland
The University of Auckland
Stewart, Alistair W.
New Zealand, Auckland
The University of Auckland
Strachan, David P.
United Kingdom, London
St George’s, University of London
Aït-Khaled, Nadia
France, Paris
Union Internationale Contre la Tuberculose et Les Maladies Respiratoires
Anderson, H. R.
United Kingdom, London
St George’s, University of London
Asher, Innes
New Zealand, Auckland
The University of Auckland
Beasley, Richard W.
New Zealand, Wellington
Medical Research Institute of new Zealand
Brunekreef, Bert A.
Netherlands, Utrecht
Institute for Risk Assessment Sciences
Cookson, William Osmond Charles M.
United Kingdom, Oxford
The Wellcome Centre for Human Genetics
Crane, Julian
New Zealand, Dunedin
Otago Medical School
Ellwood, Philippa
New Zealand, Auckland
The University of Auckland
Foliaki, Sunia
New Zealand, Wellington
Centre for Public Health Research
Keil, Ulrich
Germany, Munster
University of Münster
Lai, Christopher K.W.
Hong Kong, Hong Kong
Chinese University of Hong Kong
Mallol, Javier
Chile, Santiago
Universidad de Santiago de Chile
Robertson, Colin Francis
Australia, Melbourne
Royal Children's Hospital, Melbourne
Mitchell, Eleanor J.
New Zealand, Auckland
The University of Auckland
Montefort, Stephen R.
Malta, Malta
Belvedere
Odhiambo, Joseph A.
Kenya, Nairobi
Kenya Medical Research Institute
Pearce, Neil E.
New Zealand, Wellington
Centre for Public Health Research
Shah, Jayant R.
India, Mumbai
Jaslok Hospital and Research Centre
Stewart, Alistair William
New Zealand, Auckland
The University of Auckland
Strachan, David Peter
United Kingdom, London
St George’s, University of London
von Mutius, Erika R.M.
Germany, Munich
Klinikum Der Universität München
Weiland, Stephan Karl
Germany, Ulm
Universität Ulm
Williams, Hywel C.
United Kingdom, Nottingham
Queen's Medical Centre
Statistics
Citations: 401
Authors: 28
Affiliations: 19
Identifiers
Doi:
10.1111/j.1399-3038.2007.00601.x
ISSN:
09056157
e-ISSN:
13993038
Research Areas
Maternal And Child Health
Study Design
Cross Sectional Study