Publication Details

AFRICAN RESEARCH NEXUS

SHINING A SPOTLIGHT ON AFRICAN RESEARCH

chemical engineering

The anticancer activity of an air-stable Pd(i)-NHC (NHC = N-heterocyclic carbene) dimer

Chemical Communications, Volume 56, No. 81, Year 2020

A new dinuclear Pd(i) complex coordinating two bis(NHC) ligands revealed an unsuspected stability despite the unsaturation of the two metal centres. Even more surprisingly, the compound showed high and selective antiproliferative activity against different cancer cell lines and ovarian cancer tumoroids, and the mechanism of action was different from that of cisplatin.

Statistics
Citations: 17
Authors: 13
Affiliations: 6
Identifiers
Doi: 10.1039/d0cc03883k
ISSN: 13597345
e-ISSN: 1364548X
Research Areas
Cancer
Environmental

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