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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
Is IS
ABA-1
customized for Acinetobacter?
FEMS Microbiology Letters, Volume 243, No. 2, Year 2005
Notification
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Description
An insertion sequence (ISABA-1) was identified in Acinetobacter spp., but not in Enterobacteriacea and Pseudomonas aeruginosa. Numerous copies of the IS were identified in Acinetobacter strains containing the element. In one of the Acinetobacter baumannii strains, ISABA-1 was identified adjacent to sulII and transcription of the resistance gene is presumed to be dependent on promoter sequences within the IS. Since the IS is adjacent to ampC and blaOXA in this A. baumannii strain, it may be that IS ABA-1 plays an important role in the expression of antibiotic resistance genes in this genus. © 2005 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
Authors & Co-Authors
Segal, Heidi
South Africa, Cape Town
University of Cape Town
Garny, Seike
South Africa, Cape Town
University of Cape Town
Elisha, Brenda Gay
South Africa, Cape Town
University of Cape Town
South Africa, Observatory
Groote Schuur Hospital
Statistics
Citations: 155
Authors: 3
Affiliations: 2
Identifiers
Doi:
10.1016/j.femsle.2005.01.005
ISSN:
03781097
Research Areas
Genetics And Genomics