Reactive urticaria and severe thrombocytosis in a child with SARS-CoV-2 infection

Coronavirus SARS-CoV-2 has made a significant impact around the world through COVID-19 and its related complications. Individuals with comorbid conditions and the elderly have been at risk of significant inflammatory complications, including the cytokine release syndrome (CRS) and acute respiratory distress syndrome (ARDS). Children, on the other hand, have been less affected and have had less severe disease. However, reports from Europe and North America have described clusters of children and adolescents with paediatric multisystem inflammatory syndrome. Both adults and children have also exhibited a number of unusual disease manifestations. We present the case of a South African child, infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), presenting with reactive urticaria and thrombocytosis, further broadening the clinical spectrum of COVID-19 in children.