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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
biochemistry, genetics and molecular biology
The role of retinol-binding protein in protein-calorie malnutrition
Metabolism, Volume 24, No. 5, Year 1975
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Description
Plasma RBP is decreased to 1.62 mg ± 0.71 100 ml, or 31.1% of normal, in the acute stage of kwashiorkor. RBP doubles its plasma level after 1 wk and triples after 2 wk of appropriate refeeding. The return to normal of RPB runs in close parallel with prealbumin (PA), implying that both components remain bound by 1:1 molar ratio in the PA-RBP complex. Low values recorded on admission for RBP seem to be the result of reduced liver biosynthesis. On the other hand, a high correlation persists between RBP and retinol plasma level along the successive steps of clinical recovery, suggesting that RBP acts as the limiting factor for retinol transport. © 1975.
Authors & Co-Authors
Ingenbleek, Yves
Senegal, Dakar
Université Cheikh Anta Diop de Dakar
Belgium, Louvain-la-neuve
Faculté de Médecine et Médecine Dentaire
Van Den Schrieck, Henry George
Senegal, Dakar
Université Cheikh Anta Diop de Dakar
Belgium, Louvain-la-neuve
Faculté de Médecine et Médecine Dentaire
de Nayer, Philippe
Senegal, Dakar
Université Cheikh Anta Diop de Dakar
Belgium, Louvain-la-neuve
Faculté de Médecine et Médecine Dentaire
de Visscher, Michel G.
Senegal, Dakar
Université Cheikh Anta Diop de Dakar
Belgium, Louvain-la-neuve
Faculté de Médecine et Médecine Dentaire
Statistics
Citations: 135
Authors: 4
Affiliations: 2
Identifiers
Doi:
10.1016/0026-0495(75)90143-2
ISSN:
00260495
Research Areas
Food Security