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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
environmental science
Serum organochlorine pesticide levels in patients with colorectal cancer in egypt
Archives of Environmental Health, Volume 52, No. 6, Year 1997
Notification
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Description
The widespread use of pesticides in Egypt, the high incidence of colorectal cancer in Egyptian children and young adults, and the published U.S. case reports in which pesticides have been connected with colorectal cancer led the authors to investigate the possible association between organochlorines and colorectal cancer. The authors conducted a pilot study to describe serum organochlorine levels among 31 Egyptian colorectal patients and 17 controls. High levels and large interindividual variability of p, p'-dichloro-diphenyl-dicholoroethylene (DDE), dichloro-diphenyl-trichloroanthane (DDT), β-hexachlorocyclohexane (β-HCH), and hexachlorobenzene (HCB) levels were found among most subjects, especially those from rural areas. Farming and aging were each associated positively with high serum organochlorines. Colorectal cancer patients had higher serum organochlorines levels than controls. The high levels of organochlorines reported and their relation to age, residence, occupation, and disease status justify further study of the possible association between organochlorine pesticides and colorectal cancer in a larger population in Egypt. © 1997 Taylor & Francis Group, LLC.
Authors & Co-Authors
Soliman, Amr S.
Egypt, Shibin el Kom
Menoufia University Faculty of Medicine
United States, Houston
The University of Texas Md Anderson Cancer Center
Bondy, Melissa L.
United States, Houston
The University of Texas Md Anderson Cancer Center
Smith, Mary Ann
United States, Houston
University of Texas School of Public Health
Cooper, Sharon P.
United States, Houston
University of Texas School of Public Health
McPherson, R. Sue
United States, Houston
University of Texas School of Public Health
Ismail, Kadry
Egypt, Tanta
Tanta Cancer Center
Seifeldin, Ibrahim A.
Egypt, Tanta
Tanta Cancer Center
Khaled, Hussein Mostafa
Egypt, Giza
Cairo University
Ismail, Sohair
Egypt, Cairo
Ain Shams University
Statistics
Citations: 54
Authors: 9
Affiliations: 6
Identifiers
Doi:
10.1080/00039899709602219
ISSN:
00039896
Research Areas
Cancer
Environmental
Maternal And Child Health
Study Design
Cross Sectional Study
Cohort Study
Study Locations
Egypt