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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Detection of Chlamydia trachomatis and herpes simplex virus type 1 or 2 in cervical samples in human papilloma virus (HPV)-positive and HPV-negative women
Clinical Microbiology and Infection, Volume 12, No. 9, Year 2006
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Description
This study investigated whether the prevalence of human papilloma virus (HPV) in association with Chlamydia trachomatis, herpes simplex virus (HSV)-1 and/or HSV-2 was greater in high-grade than in low-grade or control cervical biopsy specimens. HPV-positive (n = 86) and HPV-negative (n = 213) women were screened for HPV, HSV and C. trachomatis by PCR. The most common HPV genotypes were HPV-16, HPV-6 and HPV-33; mixed HPV infection (n = 12) was also seen. A higher prevalence of C. trachomatis, HSV-1 and HSV-2 was found in HPV-positive samples. High-risk HPV genotypes and combined HPV + C. trachomatis or HPV + HSV-1, but not HSV-2, infections were associated with a greater risk of developing cervical carcinoma. © 2006 European Society of Clinical Microbiology and Infectious Diseases.
Authors & Co-Authors
Finan, Ramzi R.
Lebanon, Beirut
St. Georges University Hospital
Musharrafieh, Umayya M.
Lebanon, Beirut
American University of Beirut
Almawi, Wassim Y.
Bahrain, Manama
Arabian Gulf University
Statistics
Citations: 45
Authors: 3
Affiliations: 3
Identifiers
Doi:
10.1111/j.1469-0691.2006.01479.x
ISSN:
1198743X
e-ISSN:
14690691
Research Areas
Cancer
Study Design
Cross Sectional Study
Participants Gender
Female