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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Imaging characteristics of children with auditory neuropathy spectrum disorder
Otology and Neurotology, Volume 31, No. 5, Year 2010
Notification
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Description
OBJECTI*E:: To identify and define the imaging characteristics of children with auditory neuropathy spectrum disorder (ANSD). DESIGN:: Retrospective medical records review and analysis of both temporal bone computed tomographic (CT) and magnetic resonance images (MRI) in children with a diagnosis of ANSD. SETTING:: Tertiary referral center. PATIENTS:: One hundred eighteen children with the electrophysiologic characteristics of ANSD with available imaging studies for review. INTERVENTIONS:: Two neuroradiologists and a neurotologist reviewed each study, and consensus descriptions were established. MAIN OUTCOME MEASURES:: The type and number of imaging findings were tabulated. RESULTS:: Sixty-eight (64%) MRIs revealed at least 1 imaging abnormality, whereas selective use of CT identified 23 (55%) with anomalies. The most prevalent MRI findings included cochlear nerve deficiency (n = 51; 28% of 183 nerves), brain abnormalities (n = 42; 40% of 106 brains), and prominent temporal horns (n = 33, 16% of 212 temporal lobes). The most prevalent CT finding from selective use of CT was cochlear dysplasia (n = 13; 31%). CONCLUSION:: Magnetic resonance imaging will identify many abnormalities in children with ANSD that are not readily discernable on CT. Specifically, both developmental and acquired abnormalities of the brain, posterior cranial fossa, and cochlear nerves are not uncommonly seen in this patient population. Inner ear anomalies are well delineated using either imaging modality. Because many of the central nervous system findings identified in this study using MRI can alter the treatment and prognosis for these children, we think that MRI should be the initial imaging study of choice for children with ANSD. Copyright © 2010 Otology & Neurotology, Inc.
Authors & Co-Authors
Roche, Joseph P.
United States, Chapel Hill
196 Physician's Office Building
Huang, Benjamin Y.
United States, Chapel Hill
The University of North Carolina at Chapel Hill
Castillo, Maurício Rodríguez
United States, Chapel Hill
The University of North Carolina at Chapel Hill
Bassim, Marc Kaissar
Lebanon, Beirut
American University of Beirut Medical Center
Adunka, Oliver Franz
United States, Chapel Hill
196 Physician's Office Building
Buchman, Craig A.
United States, Chapel Hill
196 Physician's Office Building
Statistics
Citations: 73
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.1097/MAO.0b013e3181d8d528
ISSN:
15317129
e-ISSN:
15374505
Research Areas
Health System And Policy
Maternal And Child Health
Study Design
Cross Sectional Study
Cohort Study