Heterozygote advantage in cystic fibrosis: Mosquito tests
Clinical Genetics, Volume 16, No. 2, Year 1979
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Tests to demonstrate a preference by mosquitoes for stinging controls as opposed to obligate heterozygotes for Cystic Fibrosis proved negative. If a heterozygote advantage caused a lower malarial incidence in carriers in South West Africa, it must have worked through the malarial parasite being adversely affected by a serum factor. This remains to be tested.