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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
agricultural and biological sciences
Levels of Fumonisins B
1
and B
2
in Feeds Associated with Confirmed Cases of Equine Leukoencephalomalacia
Journal of Agricultural and Food Chemistry, Volume 39, No. 1, Year 1991
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Description
Leukoencephalomalacia (LEM) is a neurotoxic disease of Equidae caused by the ingestion of feed contaminated with the fungus Fusarium moniliforme. Feed samples from the United States that were fed to horses prior to the development of LEM were analyzed for fumonisin B1 (FB1) and fumonisin B2 (FB2), toxic secondary metabolites of F. moniliforme. In addition, FB1, FB2, and moniliformin were determined in corn cultures of 10 isolates of F. moniliforme from these samples. None of the cultures produced moniliformin but all contained both FB1 (160-3800 μg g−1) and FB2 (20-950 μg g−1). All 14 feed samples contained both FB1 (1.3-27.0 μg g−1) and FB2 (0.1-12.6 μg g−1). FB1 was the major fumonisin in the cultures (80-96%) as well as in the feed samples (53-93%). These results support the finding that the fumonisins are causative factors in the development of LEM in horses. © 1991, American Chemical Society. All rights reserved.
Authors & Co-Authors
Thiel, Pieter G.
South Africa, Tygerberg
South African Medical Research Council
Shephard, Gordon Seymour
South Africa, Tygerberg
South African Medical Research Council
Sydenham, Erick W.
South Africa, Tygerberg
South African Medical Research Council
Marasas, W. F. O.
South Africa, Tygerberg
South African Medical Research Council
Nelson, Paul E.
United States, University Park
Pennsylvania State University
Wilson, Terrance M.
United States, Ames
Usda Aphis National Veterinary Services Laboratories
Statistics
Citations: 142
Authors: 6
Affiliations: 3
Identifiers
Doi:
10.1021/jf00001a021
ISSN:
00218561
e-ISSN:
15205118
Research Areas
Environmental