Skip to content
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Menu
Home
About Us
Resources
Profiles Metrics
Authors Directory
Institutions Directory
Top Authors
Top Institutions
Top Sponsors
AI Digest
Contact Us
Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Holmium laser enucleation versus photoselective vaporization for prostatic adenoma greater than 60 Ml: Preliminary results of a prospective, randomized clinical trial
Journal of Urology, Volume 188, No. 1, Year 2012
Notification
URL copied to clipboard!
Description
Purpose: To our knowledge we report the first single center, prospective, randomized study comparing holmium laser enucleation and high performance GreenLight™ prostate photoselective vaporization as surgical treatment of prostatic adenomas greater than 60 ml. Materials and Methods: A total of 80 patients with a large prostatic adenoma were randomly assigned to surgical treatment with holmium laser enucleation or photoselective vaporization. International Prostate Symptom Score, International Index of Erectile Function-15, maximum flow rate, post-void residual urine, serum prostate specific antigen and transrectal ultrasound volume were recorded. Results: Patient baseline characteristics were similar for holmium laser enucleation and photoselective vaporization. Operative time and catheter removal time were almost equal in the 2 groups (p = 0.7 and 0.2, respectively). Eight vaporization cases were converted to transurethral prostate resection or holmium laser enucleation intraoperatively due to bleeding. A significantly higher maximum flow rate and lower post-void residual urine were noted in holmium laser cases during the entire followup (at 1 year each p = 0.02). However, no significant difference in International Prostate Symptom Score, quality of life or International Index of Erectile Function-15 was detected. Prostate volume and serum PSA decreased 78% and 88% in the holmium laser group, and 52% and 60% in the vaporization group, respectively. Conclusions: Holmium laser enucleation and photoselective vaporization are effective for lower urinary tract symptoms due to a large prostatic adenoma. Early subjective functional results (maximum flow rate and post-void residual urine) of holmium laser enucleation appear to be superior to those of photoselective vaporization. In our hands cases intended to be treated with photoselective vaporization were at 22% risk of conversion to another modality. This could reflect our determination to vaporize to the capsule in all vaporization cases. © 2012 American Urological Association Education and Research, Inc.
Authors & Co-Authors
Elmansy, Hazem M.
Canada, Montreal
Université Mcgill
Baazeem, Abdulaziz
Canada, Montreal
Université Mcgill
Kotb, Ahmed Fouad
Canada, Montreal
Université Mcgill
Badawy, Hesham A.
Egypt, Cairo
Faculty of Medicine
Riad, Essam
Egypt, Giza
Theodor Bilharz Research Institute
Emran, Ashraf Mohamed
Egypt, Cairo
Faculty of Medicine
Elhilali, Mostafa M.
Canada, Montreal
Université Mcgill
Statistics
Citations: 109
Authors: 7
Affiliations: 3
Identifiers
Doi:
10.1016/j.juro.2012.02.2576
ISSN:
00225347
e-ISSN:
15273792
Research Areas
Disability
Health System And Policy
Sexual And Reproductive Health
Study Design
Randomised Control Trial
Cohort Study