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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
chemical engineering
Synthesis and fungicidal activity of new N,O-acyl chitosan derivatives
Biomacromolecules, Volume 5, No. 2, Year 2004
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Description
Novel N,O-acyl chitosan (NOAC) derivates were synthesized to examine their fungicidal activity against the-gray mould fungus Botrytis cinerea (Leotiales: Sclerotiniaceae) and the rice leaf blast fungus Pyricularia oryzae (Teleomorph: Magnaporth grisea). The fungicidal activity was evaluated by the radial growth bioassay. NOAC derivatives were more active against the two plant pathogens than chitosan itself, and the effect was concentration dependent. Against B. cinerea, 4-chlorobutyryl chitosan (EC50 = 0.043%), decanoyl chitosan (EC50 = 0.044%), cinnamoyl chitosan (EC50 = 0.045%, and p-methoxybenzoyl chitosan (EC50 = 0.050%) were the most active (12-13-fold more active than chitosan). (Un)-substituted benzoyl chitosan derivatives were more active against B. cinerea than most of these with N,O-alkyl derivatives. Against P. oryzae chitosan derivatives with lauroyl, methoxy acetyl, methacryloyl and decanoyl were the most active. © 2004 American Chemical Society.
Authors & Co-Authors
Badawy, Mohamed E.I.
Belgium, Ghent
Universiteit Gent
Rabea, Entsar I.
Belgium, Ghent
Universiteit Gent
Rogge, Tina M.
Belgium, Ghent
Universiteit Gent
Stevens, Christian V.
Belgium, Ghent
Universiteit Gent
Smagghe, Guy J.
Belgium, Ghent
Universiteit Gent
Steurbaut, Walter
Belgium, Ghent
Universiteit Gent
Höfte, Monica M.
Belgium, Ghent
Universiteit Gent
Statistics
Citations: 150
Authors: 7
Affiliations: 1
Identifiers
Doi:
10.1021/bm0344295
ISSN:
15257797