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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Acute kidney injury related to pregnancy in developing countries: Etiology and risk factors in an intensive care unit
Journal of Nephrology, Volume 25, No. 5, Year 2012
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Description
Background: The aim of this study was to determine etiologies, risk factors and prognosis of pregnancy-related acute kidney injury (AKI) in an intensive care unit. Methods: Patients included in this retrospective study had a gestational age exceeding 20 weeks of amenorrhea. We defined and classified AKI according to the criteria of the RIFLE classification. Patients were separated into 2 groups: group 1 with AKI and group 2 without AKI. Results: Obstetric admission cases (n=137) were compiled, including 46 cases of AKI. Comparison of the different variables between groups 1 and 2 revealed a statistically significant difference regarding home birth (p=0.004), severe hypotension (p=0.007), icterus (p=0.001), oligoanuria (p=0.001), hyperuricemia (p=0.01), thrombopenia (p=0.001) and hepatic cytolysis (p=0.001). The incidences of HELLP syndrome, abruptio placentae and disseminated intravascular coagulation were higher in the AKI group. Maternal mortality was 28.3% in group 1. Conclusion: The incidence of AKI in developing countries ranges from 4% to 36% depending on the study. In India and Pakistan, cases of pregnancy-related AKI occur mainly during the first trimester of pregnancy and are related to severe states of sepsis. In Morocco, AKI occurs mainly in the third trimester in a context of hypertensive disorders. Maternal mortality varies between 6% and 30% depending on the study. AKI is a frequently occurring complication in developing countries. It is reversible as shown by total recovery of renal function, but this depends on early and appropriate diagnosis and treatment. Nevertheless, the best treatment remains prevention. © 2011 Società Italiana di Nefrologia.
Authors & Co-Authors
Bentata, Yassamine
Morocco, Oujda
Université Mohammed Premier Oujda
Housni, Brahim
Morocco, Oujda
Université Mohammed Premier Oujda
Mimouni, Ahmed
Morocco, Oujda
Université Mohammed Premier Oujda
Azzouzi, Abderrahim A.
Morocco, Oujda
Université Mohammed Premier Oujda
Abouqal, Redouane
Morocco, Agdal Rabat
Ibn Sina Hospital, Agdal Rabat
Morocco, Rabat
Mohammed V University in Rabat
Statistics
Citations: 64
Authors: 5
Affiliations: 3
Identifiers
Doi:
10.5301/jn.5000058
ISSN:
11218428
e-ISSN:
17246059
Research Areas
Maternal And Child Health
Noncommunicable Diseases
Sexual And Reproductive Health
Violence And Injury
Study Design
Cohort Study
Study Locations
Morocco