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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Detection of hepatitis B virus infection markers in dried plasma spots among patients in Congo-Brazzaville
Diagnostic Microbiology and Infectious Disease, Volume 78, No. 3, Year 2014
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Description
The detection of hepatitis B virus (HBV) infection markers by using dried plasma spots from 32 patients living in Congo has been assessed. Considering frozen plasma samples as gold standard, the sensitivity and specificity of HBV serologic markers detection in dried plasma eluted from filter paper were 100%. The sensitivity and the specificity of HBV DNA detection reached 96% and 100%, respectively, with plasma samples dried on filter paper compared to standard samples. Dried plasma samples can represent an alternative to conventional sampling for HBV detection and management of the infection in developing countries. © 2014 Elsevier Inc.
Authors & Co-Authors
Alidjinou, Enagnon Kazali
France, Lille
Laboratoire de Virologie
Moukassa, Donatien
Congo
Hôpital Général de Loandjili
Sane, F.
France, Lille
Laboratoire de Virologie
Twagirimana Nyenyeli, Séraphin
Congo
Hôpital Général de Loandjili
Akoko, Estina Chandrelle
Congo
Hôpital Général de Loandjili
Mountou, Michèle Valy
Congo
Hôpital Général de Loandjili
Bocket, Laurence
France, Lille
Laboratoire de Virologie
Ibara, Jean Rosaire
Congo, Brazzaville
Centre Hospitalier et Universitaire de Brazzaville
Hober, Didier
France, Lille
Laboratoire de Virologie
Statistics
Citations: 9
Authors: 9
Affiliations: 3
Identifiers
Doi:
10.1016/j.diagmicrobio.2013.09.019
ISSN:
07328893
Research Areas
Genetics And Genomics
Infectious Diseases
Study Locations
Congo