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Publication Details
AFRICAN RESEARCH NEXUS
SHINING A SPOTLIGHT ON AFRICAN RESEARCH
medicine
Factors influencing visual and clinical outcome in Nigerian patients with cranial meningioma
Journal of Clinical Neuroscience, Volume 13, No. 6, Year 2006
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Description
We retrospectively analysed the impact of selected clinicopathological factors on visual and clinical outcome in patients with histologically verified cranial meningioma. The 60 patients analysed for tumour characteristics consisted of 32 females and 28 males (sex ratio 1.1:1) aged 9-77 years (mean 40 years) seen between 1977 and 1999 at the University College Hospital, Ibadan, Nigeria. The patients for whom sufficient clinical data was available (n = 35) presented within 2-60 months (mean 18 months) of symptom onset with large tumours (mean size 52 mm), and perifocal oedema (26/35), poor vision, focal neurological deficits, seizures and clinical evidence of intracranial hypertension. The most common tumour site was the convexity. There was loss of vision in 30/35 (85.7%) patients. Loss of vision was significantly related to tumour site and tumour size as well as perifocal oedema, (P < 0.05). The case-mortality rate was 11.4% at 1 month and 20% at 6 months post-operation and was significantly correlated with intracranial hypertension. Neither age nor sex affected the outcome (P > 0.05). © 2006 Elsevier Ltd. All rights reserved.
Authors & Co-Authors
Odebode, Timothy Olugbenga
Nigeria, Ibadan
University of Ibadan
Akang, Effiong E.U.
Nigeria, Ibadan
University of Ibadan
Shokunbi, Mathew Temitayo
Nigeria, Ibadan
University of Ibadan
Malamo, A. O.
Nigeria, Ibadan
University of Ibadan
Ogunseyinde, Ayotunde Oluremi
Nigeria, Ibadan
University of Ibadan
Statistics
Citations: 20
Authors: 5
Affiliations: 1
Identifiers
Doi:
10.1016/j.jocn.2005.07.023
ISSN:
09675868
Research Areas
Cancer
Health System And Policy
Noncommunicable Diseases
Study Locations
Nigeria
Participants Gender
Female